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BCH 6107
Biophysical Techniques in Proteomics and Protein Science
Spring
MWF 3rd period/R3-265
 
Course Coordinator: Robert McKenna
Room: LG 179
Phone: 392-5696
E-mail: rmckenna@ufl.edu

Introduction: In the years following the sequencing of the human genome, biomedical science has found that sequence isnt everything. The genome can only describe the possible, while the proteome can describe the actual. The study of proteomics includes the profiling of all the proteins expressed by a given tissue or cell, including regulatory modifications and protein-protein interactions. The field of proteomics is as rapidly progressive and far-reaching as genomic study once was, spawning numerous technological advances. Given the interdisciplinary nature of protein science and the many new innovations in proteomics, there is a demonstrable need for a course which educates students on the theory and application of relevant techniques.

This course will discuss the theory and application of modern biophysical techniques relevant to proteomics and protein science. Techniques covered will include multi-dimensional gel electrophoresis, liquid chromatography, and mass spectroscopy. Sample preparation, technique selection, and data analysis will also be covered. Emphasis will be placed on efficient use of these techniques to a given research application and the combination of these analyses to increase investigative power.

Additionally, students will be able to readily incorporate these techniques into their research, as the Interdisciplinary Center for Biotechnology Research (ICBR) possesses cutting-edge technology for these very applications. This course is targeted to graduate students in the Interdisciplinary Program in Biomedical Sciences (primarily 2nd Semester 1st year students or 2nd year students).
 
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