Research labs in the department are extremely well equipped for the individual research needs of faculty and students with instruments dedicated to their individual research needs. In addition, members of the department have access to state-of-the-art core facilities that house multi-user instruments and provide a variety of analytical services. The equipment includes HPLC's, FPLC's, steady-state fluorimeters, life-time fluorimeters with laser excitation, UV/VIS spectrophotometers, ultracentrifuges, high resolution magnets for structure determination and imaging, X-ray facilities, sophisticated computing systems for analyzing structural and imaging data as well as modeling, and thermocyclers in addition to standard molecular and biochemical equipment.

Center for Mammalian Genetics -

The CMG is organized to support, facilitate and enhance interdisciplinary research and training in the broad area of mammalian genetics in the UF College of Medicine. Major areas of research interest and activity by CMG members include epigenetics, human and mouse genetics, mouse models of human disease, gene regulation, genomic imprinting, Prader-Willi and Angelman syndromes, mammalian development, viral genetics, microarray analysis, genomics, etc. The CMG also provides a variety of services to researchers in genetics. In addition, the CMG organizes and supports a weekly seminar series on mammalian genetics that include distinguished outside speakers. The Center provides and maintains common items of large equipment for daily use by CMG members. These services and facilities all serve to advance the research and education missions of the College of Medicine in the rapidly evolving field of mammalian genetics.

Evelyn F. & William L. McKnight Brain Institute -

The Advanced Magnetic Resonance Imaging and Spectroscopy Facility has five NMR magnet systems (500 and 600 MHz NMR spectrometers, 750 MHz wide bore spectrometer, and 4.7T/200 MHz and 11T/500 MHz MRI spectrometers) are available for high-resolution molecular structure determination and in vivo imaging and spectroscopy applications. The X-ray facility has a Rigaku generator, R-AXIS IV++ imaging plate system, osmic mirrors and an oxford cryosystem cryostream.

Interdisciplinary Center for Biotechnology Research -

Instrumentation and services available through core labs: A variety of instrumentation including 2D gel electrophoresis systems, a BiaCore surface plasmon resonance instrument, a real-time PCR instrument and a Molecular Dynamics Typhoon Phosphorimager are available for use. In addition the core labs offer a variety of services including peptide/protein sequencing, protein identification by MALDI TOF and ESI mass spectrometry, peptide synthesis, DNA sequencing, microarray analysis, electron microscopy, and monoclonal antibody preparation. Workshops on new technologies are routinely offered through the core facilities.

Additional Affiliated Centers and Institutes-

Center for Structural Biology

Genetics Institute at the University of Florida

Powell Gene Therapy Center

University of Florida Shands Cancer Center