Thomas Mareci, Ph.D.

Professor

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Research: Structure and Function in the Nervous System

Ph.D. from Oxford University, 1982

 

Contact Information:

     Office: LG-183 McKnight Brain Institute
     Lab: LG-152 McKnight Brain Institute
     Telephone: (352) 273-5348
     Email: thmareci@ufl.edu

BIOGRAPHY

Professor Mareci received a doctoral degree in physical chemistry in 1982 from Oxford University for his work on nuclear magnetic resonance multiple-quantum spectroscopy.  Dr. Mareci joined the faculty of the University of Florida in 1982 and served as the Director of the Center for Structural Biology from 1993-2007.  He is an affiliate faculty member of the Departments of Physics and Biomedical Engineering and a member of the National High Magnetic Field Laboratory, where he is helping to develop the in vivo magnetic resonance program.  He has published over 80 journal articles and 12 book chapters.

RESEARCH DESCRIPTION

Dr. Mareci studies tissue structure and biochemical processes in the nervous system using nuclear magnetic resonance (NMR). His current projects are:  1) Image nervous tissue fiber structure in white and gray matter (see figure below of human brain in vivo) and measure functional connectivity between gray matter regions.  2) Study convection drug delivery into the nervous system using dynamic contrast enhanced MR imaging in vivo.  3) Design and construct unique MR coils with enhancement sensitivity to allow the acquisition of very high spatial-resolution MR images and spectra.  Future work will be directed toward the NMR measurement in vivo of a neurochemical profile of the brain for the study of nervous system disorders, like epilepsy.   His students come from diverse disciplines: biochemistry, biomedical and electrical engineering, chemistry, neuroscience, and physics.