Charlie Khemtong

Charlie Khemtong, PhD

Associate Professor

Department: MD-ENDOCRINOLOGY
Business Phone: (352) 273-8646

About Charlie Khemtong

Dr. Chalermchai “Charlie” Khemtong is a chemist by training. He received his B.Sc. from Ubonratchathani University in Thailand and his Ph.D. from the University of Akron. He completed his postdoctoral training at the University of Texas Southwestern Medical Center (UT Southwestern), where he later rose to the rank of assistant professor in the Advanced Imaging Research Center. Dr. Khemtong joined the University of Florida faculty as an associate professor in the summer of 2020. The research in Dr. Khemtong’s group is focused on understanding intermediary metabolism using stable isotope tracers, primarily carbon-13, combined with magnetic resonance and mass spectrometry techniques. His group is also developing novel imaging methods to detect metabolic abnormalities associated with diseases such as diabetes, nonalcoholic fatty liver disease, and cancer.

Teaching Profile

Courses Taught
2020,2022-2023
BCH6208 Advanced Metabolism: Regulation of Key Reactions in Carbohydrate and Lipid Metabolism
2020
BCH6207 Advanced Metabolism: Role of Membranes in Signal Transduction and Metabolic Control
2020-2023
BCH6206 Advanced Metabolism
2021,2023
BCH4905 Biochemistry Senior Research

Clinical Profile

Specialties
  • Endocrinology, Diabetes and Metabolism

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-1976-8098

Publications

2022
Oxidation of hyperpolarized [1‐ 13 C]pyruvate in isolated rat kidneys
NMR in Biomedicine. [DOI] 10.1002/nbm.4857.
2021
Co-Polarized [1-13C]Pyruvate and [1,3-13C2]Acetoacetate Provide a Simultaneous View of Cytosolic and Mitochondrial Redox in a Single Experiment
ACS Sensors. 6(11):3967-3977 [DOI] 10.1021/acssensors.1c01225. [PMID] 34761912.
2020
Mitochondrial substrate utilization regulates cardiomyocyte cell-cycle progression
Nature Metabolism. 2(2):167-178 [DOI] 10.1038/s42255-020-0169-x.
2019
Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency
Science Translational Medicine. 11(480) [DOI] 10.1126/scitranslmed.aan0457. [PMID] 30787166.
2019
Metabolism of hyperpolarized13C‐acetoacetate to β‐hydroxybutyrate detects real‐time mitochondrial redox state and dysfunction in heart tissue
NMR in Biomedicine. 32(6) [DOI] 10.1002/nbm.4091. [PMID] 30968985.
2019
Probing carbohydrate metabolism using hyperpolarized13C‐labeled molecules
NMR in Biomedicine. 32(10) [DOI] 10.1002/nbm.4018. [PMID] 30474153.
2019
Real-time hyperpolarized 13C magnetic resonance detects increased pyruvate oxidation in pyruvate dehydrogenase kinase 2/4–double knockout mouse livers
Scientific Reports. 9(1) [DOI] 10.1038/s41598-019-52952-6. [PMID] 31712597.
2018
Esterase-Catalyzed Production of Hyperpolarized 13C-Enriched Carbon Dioxide in Tissues for Measuring pH
ACS Sensors. 3(11):2232-2236 [DOI] 10.1021/acssensors.8b01097. [PMID] 30398335.

Grants

Jul 2020 ACTIVE
Esterase-Sensitive Hyperpolarized 13C Probes for Simultaneous Imaging of pH and Energy Metabolism
Role: Principal Investigator
Funding: NATL INST OF HLTH NIBIB

Education

Doctor of Philosophy in Chemistry
2001-2005 · University of Akron
Bachelor of Science in Chemistry
1996-2000 · Ubonratchathani University

Contact Details

Phones:
Business:
(352) 273-8646
Addresses:
Business Mailing:
PO Box 100226
GAINESVILLE FL 32610