Jennifer S Stancill

Jennifer S Stancill,

Department: MD-BIOCHEMISTRY-GENERAL

Publications

2023
Hydrogen peroxide detoxification through the peroxiredoxin/thioredoxin antioxidant system: A look at the pancreatic β-cell oxidant defense.
Vitamins and hormones. 121:45-66 [DOI] 10.1016/bs.vh.2022.11.001. [PMID] 36707143.
2023
β-cell-selective inhibition of DNA damage response signaling by nitric oxide is associated with an attenuation in glucose uptake.
The Journal of biological chemistry. 299(3) [DOI] 10.1016/j.jbc.2023.102994. [PMID] 36773802.
2022
Cytokine and Nitric Oxide-Dependent Gene Regulation in Islet Endocrine and Nonendocrine Cells.
Function (Oxford, England). 3(1) [DOI] 10.1093/function/zqab063. [PMID] 34927076.
2022
Deletion of Thioredoxin Reductase Disrupts Redox Homeostasis and Impairs β-Cell Function.
Function (Oxford, England). 3(4) [DOI] 10.1093/function/zqac034. [PMID] 35873655.
2021
Regulation of ATR-dependent DNA damage response by nitric oxide.
The Journal of biological chemistry. 296 [DOI] 10.1016/j.jbc.2021.100388. [PMID] 33567339.
2021
Single-cell RNA sequencing of mouse islets exposed to proinflammatory cytokines.
Life science alliance. 4(6) [DOI] 10.26508/lsa.202000949. [PMID] 33883217.
2021
Suppressive neutrophils require PIM1 for metabolic fitness and survival during chronic viral infection.
Cell reports. 35(8) [DOI] 10.1016/j.celrep.2021.109160. [PMID] 34038722.
2021
The Role of Thioredoxin/Peroxiredoxin in the β-Cell Defense Against Oxidative Damage.
Frontiers in endocrinology. 12 [DOI] 10.3389/fendo.2021.718235. [PMID] 34557160.
2020
Excitotoxicity and Overnutrition Additively Impair Metabolic Function and Identity of Pancreatic β-Cells.
Diabetes. 69(7):1476-1491 [DOI] 10.2337/db19-1145. [PMID] 32332159.
2020
Peroxiredoxin 1 plays a primary role in protecting pancreatic β-cells from hydrogen peroxide and peroxynitrite.
American journal of physiology. Regulatory, integrative and comparative physiology. 318(5):R1004-R1013 [DOI] 10.1152/ajpregu.00011.2020. [PMID] 32292063.
2020
The location of sensing determines the pancreatic β-cell response to the viral mimetic dsRNA.
The Journal of biological chemistry. 295(8):2385-2397 [DOI] 10.1074/jbc.RA119.010267. [PMID] 31915247.
2019
Pancreatic β-cells detoxify H2O2 through the peroxiredoxin/thioredoxin antioxidant system.
The Journal of biological chemistry. 294(13):4843-4853 [DOI] 10.1074/jbc.RA118.006219. [PMID] 30659092.
2019
Transgene-associated human growth hormone expression in pancreatic β-cells impairs identification of sex-based gene expression differences.
American journal of physiology. Endocrinology and metabolism. 316(2):E196-E209 [DOI] 10.1152/ajpendo.00229.2018. [PMID] 30532991.
2018
Nitric oxide antagonism to glioblastoma photodynamic therapy and mitigation thereof by BET bromodomain inhibitor JQ1.
The Journal of biological chemistry. 293(14):5345-5359 [DOI] 10.1074/jbc.RA117.000443. [PMID] 29440272.
2017
Chronic β-Cell Depolarization Impairs β-Cell Identity by Disrupting a Network of Ca2+-Regulated Genes.
Diabetes. 66(8):2175-2187 [DOI] 10.2337/db16-1355. [PMID] 28550109.
2016
Pancreatic Inflammation Redirects Acinar to β Cell Reprogramming.
Cell reports. 17(8):2028-2041 [DOI] 10.1016/j.celrep.2016.10.068. [PMID] 27851966.
2014
Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.
Cell metabolism. 20(6):979-90 [DOI] 10.1016/j.cmet.2014.11.004. [PMID] 25470546.

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