Qun Tang,
POSTDOC ASO
Publications
2023
Structures of LIG1 active site mutants reveal the importance of DNA end rigidity for mismatch discrimination.
Research square.
[DOI] 10.21203/rs.3.rs-2720903/v1.
[PMID] 37090517.
2022
Structures of LIG1 that engage with mutagenic mismatches inserted by polβ in base excision repair.
Nature communications.
13(1)
[DOI] 10.1038/s41467-022-31585-w.
[PMID] 35790757.
2021
DNA ligase I fidelity mediates the mutagenic ligation of pol β oxidized and mismatch nucleotide insertion products in base excision repair.
The Journal of biological chemistry.
296
[DOI] 10.1016/j.jbc.2021.100427.
[PMID] 33600799.
2021
The scaffold protein XRCC1 stabilizes the formation of polβ/gap DNA and ligase IIIα/nick DNA complexes in base excision repair.
The Journal of biological chemistry.
297(3)
[DOI] 10.1016/j.jbc.2021.101025.
[PMID] 34339737.
2020
DNA ligase I variants fail in the ligation of mutagenic repair intermediates with mismatches and oxidative DNA damage.
Mutagenesis.
35(5):391-404
[DOI] 10.1093/mutage/geaa023.
[PMID] 32914844.
Contact Details
Phones:
- Business:
- (352) 294-8391
Emails:
- Business:
- tangqun@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100245
GAINESVILLE FL 32610 - Business Street:
-
ARB, R3-171
1200 NEWELL DRIVE, ARB, R3-171
1200 NEWELL DRIVE
GAINESVILLE FL 32610