Qun Tang

Qun Tang,

POSTDOC ASO

Department: MD-BIOCHEMISTRY-GENERAL
Business Phone: (352) 294-8391
Business Email: tangqun@ufl.edu

Publications

2024
Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in the Base Excision Repair Pathway.
Journal of molecular biology. 436(4) [DOI] 10.1016/j.jmb.2023.168410. [PMID] 38135179.
2023
Structures of LIG1 active site mutants reveal the importance of DNA end rigidity for mismatch discrimination.
Research square. [DOI] 10.21203/rs.3.rs-2720903/v1. [PMID] 37090517.
2022
Structures of LIG1 that engage with mutagenic mismatches inserted by polβ in base excision repair.
Nature communications. 13(1) [DOI] 10.1038/s41467-022-31585-w. [PMID] 35790757.
2021
DNA ligase I fidelity mediates the mutagenic ligation of pol β oxidized and mismatch nucleotide insertion products in base excision repair.
The Journal of biological chemistry. 296 [DOI] 10.1016/j.jbc.2021.100427. [PMID] 33600799.
2021
The scaffold protein XRCC1 stabilizes the formation of polβ/gap DNA and ligase IIIα/nick DNA complexes in base excision repair.
The Journal of biological chemistry. 297(3) [DOI] 10.1016/j.jbc.2021.101025. [PMID] 34339737.
2020
DNA ligase I variants fail in the ligation of mutagenic repair intermediates with mismatches and oxidative DNA damage.
Mutagenesis. 35(5):391-404 [DOI] 10.1093/mutage/geaa023. [PMID] 32914844.

Contact Details

Phones:
Business:
(352) 294-8391
Emails:
Business:
tangqun@ufl.edu
Addresses:
Business Mailing:
PO Box 100245
GAINESVILLE FL 32610
Business Street:
ARB, R3-171
1200 NEWELL DRIVE, ARB, R3-171
1200 NEWELL DRIVE
GAINESVILLE FL 32610