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UF Health University of Florida
Department of Biochemistry and Molecular Biology College of Medicine
Qun Tang

Qun Tang,

Biological Scientist III

Department: MD-BIOCHEM – MOLECULAR BIOL
Business Phone: (352) 294-8389
Business Email: tangqun@ufl.edu

On This Page

Publications

Academic Articles

  1. Structures of LIG1 uncover the mechanism of sugar discrimination against 5′-RNA-DNA junctions during ribonucleotide excision repair.

    Journal
    The Journal of biological chemistry.
    Volume/Issue
    300(9)
    [DOI]
    10.1016/j.jbc.2024.107688.
    [PMID]
    39159820.
    5 citations PubMed Publisher’s Site

  2. Impact of DNA ligase 1 and IIIα interactions with APE1 and polβ on the efficiency of base excision repair pathway at the downstream steps.

    Journal
    The Journal of biological chemistry.
    Volume/Issue
    300(6)
    [DOI]
    10.1016/j.jbc.2024.107355.
    [PMID]
    38718860.
    10 citations PubMed Publisher’s Site

  3. Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in the Base Excision Repair Pathway.

    Journal
    Journal of molecular biology.
    Volume/Issue
    436(4)
    [DOI]
    10.1016/j.jmb.2023.168410.
    [PMID]
    38135179.
    5 citations PubMed Publisher’s Site

  4. Structures of LIG1 active site mutants reveal the importance of DNA end rigidity for mismatch discrimination.

    Journal
    Research square.
    [DOI]
    10.21203/rs.3.rs-2720903/v1.
    [PMID]
    37090517.
    PubMed Publisher’s Site

  5. Structures of LIG1 that engage with mutagenic mismatches inserted by polβ in base excision repair.

    Journal
    Nature communications.
    Volume/Issue
    13(1)
    [DOI]
    10.1038/s41467-022-31585-w.
    [PMID]
    35790757.
    20 citations PubMed Publisher’s Site

  6. The scaffold protein XRCC1 stabilizes the formation of polβ/gap DNA and ligase IIIα/nick DNA complexes in base excision repair.

    Journal
    The Journal of biological chemistry.
    Volume/Issue
    297(3)
    [DOI]
    10.1016/j.jbc.2021.101025.
    [PMID]
    34339737.
    22 citations PubMed Publisher’s Site

  7. DNA ligase I fidelity mediates the mutagenic ligation of pol β oxidized and mismatch nucleotide insertion products in base excision repair.

    Journal
    The Journal of biological chemistry.
    Volume/Issue
    296
    [DOI]
    10.1016/j.jbc.2021.100427.
    [PMID]
    33600799.
    21 citations PubMed Publisher’s Site

  8. DNA ligase I variants fail in the ligation of mutagenic repair intermediates with mismatches and oxidative DNA damage.

    Journal
    Mutagenesis.
    Volume/Issue
    35(5):391-404
    [DOI]
    10.1093/mutage/geaa023.
    [PMID]
    32914844.
    20 citations PubMed Publisher’s Site

Contact Details

Phones:
Business:
(352) 294-8389
Emails:
Business:
tangqun@ufl.edu
Addresses:
Business Mailing:
PO Box 100245
 GAINESVILLE FL 32610
Business Street:
ARB, R3-136
1200 Newell Dr
 GAINESVILLE FL 32610