Mukundan Ragavan

Mukundan Ragavan,

Department: MD-BIOCHEMISTRY-GENERAL
Business Phone: (352) 294-8398
Business Email: mukundan@ufl.edu

Teaching Profile

Courses Taught
2020-2021
BCH6206 Advanced Metabolism
2021
BCH4905 Biochemistry Senior Research
2021
BCH6740 Physical Biochemistry/Structural Biology
2021
BCH6747 Structural Biology/Advanced Physical Biochemistry: Spectroscopy and Hydrodynamics
2020
BCH6208 Advanced Metabolism: Regulation of Key Reactions in Carbohydrate and Lipid Metabolism
2020
BCH6207 Advanced Metabolism: Role of Membranes in Signal Transduction and Metabolic Control

Research Profile

Open Researcher and Contributor ID (ORCID)

Publications

2023
Observing exocrine pancreas metabolism using a novel pancreas perfusion technique in combination with hyperpolarized [1-13 C]pyruvate.
Magnetic resonance in chemistry : MRC. 61(12):748-758 [DOI] 10.1002/mrc.5382. [PMID] 37482899.
2022
Detecting de novo Hepatic Ketogenesis Using Hyperpolarized [2-13C] Pyruvate.
Frontiers in physiology. 13 [DOI] 10.3389/fphys.2022.832403. [PMID] 35197867.
2022
Ex Vivo Hepatic Perfusion Through the Portal Vein in Mouse.
Journal of visualized experiments : JoVE. (181) [DOI] 10.3791/63154. [PMID] 35343950.
2022
In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma.
Science advances. 8(50) [DOI] 10.1126/sciadv.abp8293. [PMID] 36525494.
2022
INCA 2.0: A tool for integrated, dynamic modeling of NMR- and MS-based isotopomer measurements and rigorous metabolic flux analysis.
Metabolic engineering. 69:275-285 [DOI] 10.1016/j.ymben.2021.12.009. [PMID] 34965470.
2022
Metabolic signatures associated with oncolytic myxoma viral infections.
Scientific reports. 12(1) [DOI] 10.1038/s41598-022-15562-3. [PMID] 35871072.
2021
Application of Carbon-13 Isotopomer Analysis to Assess Perinatal Myocardial Glucose Metabolism in Sheep.
Metabolites. 11(1) [DOI] 10.3390/metabo11010033. [PMID] 33466367.
2021
Comparison of selective excitation and multi-echo chemical shift encoding for imaging of hyperpolarized [1-13C]pyruvate.
Journal of magnetic resonance (San Diego, Calif. : 1997). 325 [DOI] 10.1016/j.jmr.2021.106927. [PMID] 33607386.
2021
Deuterated water imaging of the rat brain following metabolism of [2 H7 ]glucose.
Magnetic resonance in medicine. 85(6):3049-3059 [DOI] 10.1002/mrm.28700. [PMID] 33576535.
2021
Hyperpolarized Dihydroxyacetone Is a Sensitive Probe of Hepatic Gluconeogenic State.
Metabolites. 11(7) [DOI] 10.3390/metabo11070441. [PMID] 34357335.
2021
Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease.
Molecular metabolism. 45 [DOI] 10.1016/j.molmet.2020.101154. [PMID] 33359401.
2019
Kinetic Analysis of Hepatic Metabolism Using Hyperpolarized Dihydroxyacetone.
Journal of chemical information and modeling. 59(1):605-614 [DOI] 10.1021/acs.jcim.8b00745. [PMID] 30602117.
2019
Nuclear Magnetic Resonance Measurement of Metabolic Flux Using 13C and 1H Signals.
Methods in molecular biology (Clifton, N.J.). 1996:29-40 [DOI] 10.1007/978-1-4939-9488-5_3. [PMID] 31127544.
2017
A comprehensive analysis of myocardial substrate preference emphasizes the need for a synchronized fluxomic/metabolomic research design.
American journal of physiology. Heart and circulatory physiology. 312(6):H1215-H1223 [DOI] 10.1152/ajpheart.00016.2017. [PMID] 28411229.
2017
Real-Time Analysis of Folding upon Binding of a Disordered Protein by Using Dissolution DNP NMR Spectroscopy.
Angewandte Chemie (International ed. in English). 56(25):7070-7073 [DOI] 10.1002/anie.201700464. [PMID] 28508552.
2016
Site specific polarization transfer from a hyperpolarized ligand of dihydrofolate reductase.
Journal of biomolecular NMR. 65(1):41-8 [DOI] 10.1007/s10858-016-0037-x. [PMID] 27189223.
2015
Application of blind source separation to real-time dissolution dynamic nuclear polarization.
Analytical chemistry. 87(2):1004-8 [DOI] 10.1021/ac503475c. [PMID] 25506716.
2015
Hyperpolarized (13)C Magnetic Resonance and Its Use in Metabolic Assessment of Cultured Cells and Perfused Organs.
Methods in enzymology. 561:73-106 [DOI] 10.1016/bs.mie.2015.04.006. [PMID] 26358902.
2013
Protein folding studied by dissolution dynamic nuclear polarization.
Angewandte Chemie (International ed. in English). 52(35):9192-5 [DOI] 10.1002/anie.201301851. [PMID] 23857756.
2011
Solution NMR of polypeptides hyperpolarized by dynamic nuclear polarization.
Analytical chemistry. 83(15):6054-9 [DOI] 10.1021/ac201122k. [PMID] 21651293.

Contact Details

Phones:
Business:
(352) 294-8398
Emails:
Business:
mukundan@ufl.edu
Addresses:
Business Mailing:
PO Box 100245
GAINESVILLE FL 32610
Business Street:
1200 NEWELL DRIVE, R3-244
GAINESVILLE FL 326110001