Publications

2026

January

• Bernardi F, Torrejon J, Basili I, Van Ommeren R, Marsaud V, Yu H, Talbot J, Souphron J, Indersie E, Forget A, Bonneau B, Massiot A, Alcazar C, Figeac L, Bonerandi E, Cancila G, Sirbu O, Yadav N, Mohanakrishnan D, Lombard B, Loew D, Poullet P, Liva S, Lovino M, Lin IH, Nakashima T, Gharsalli T, Nicolas PA, Yubuki N, Ribas RA, Colsch B, Chu-Van E, Castelli F, Sampaio JL, Leboucher S, Lasgi C, Besse L, Soler MN, Lo Re V, Planque N, Abeysundara N, Balin P, Wang H, Su H, Wu X, Cavalli FMG, Saulnier O, Ficarra E, Di Marcotullio L, Kumegawa K, Maruyama R, Kawauchi D, Picard D, Remke M, Riffaud L, Puiseux C, Bouchoucha Y, Huybrechts S, Simbozel M, Bourdeaut F, Varlet P, Puget S, Blauwblomme T, Andrianteranagna M, Planchon JM, Dugourd A, Saez-Rodriguez J, Barillot E, Servant N, Martignetti L, Rich J, Kool M, Pfister SM, Agnihotri S, Suzuki H, Fanjul M, Wang WJ, Tsai JW, Sun RC, Beccaria K, Dufour C, Sarry JE, Michealraj KA, Taylor MD, Ayrault O. Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma. Cancer Cell. 2026 Jan 15. Epub ahead of print. 
• Yeh YY, Lin HY, Guo J, Sun RC, Jiang S, Bian J, Dai H. Inferring high-fat dietary patterns from electronic health record data using machine learning. JAMIA Open. 2026 Jan 7. 
• Mayer-Blackwell K, Minervina A, Pogorelyy M, Rawat P, Shapiro MR, Peters LD, Ford ES, Posgai AL, Vegesana K, Minot S, Koelle DM, Greiff V, Bradley P, Brusko TM, Thomas PG, Fiore-Gartland A. TCR2HLA: Calibrated inference of HLA genotypes from TCR repertoires enables identification of immunologically relevant metaclonotypes. PLoS Comput Biol. 2026 Jan 16. 
• Shea SA, Scheer FAJL, Gumz ML, Eikenberry S, Qian J, Thosar SS, Sole MJ, Martino TA. Unlocking the Potential of Circadian Biology for Cardiovascular Health. Physiol Rev. 2026 Jan 7. Epub ahead of print. 

2025

December

• Mills MN, Pacheo G, Tong AY, Tong EL, Hannani MA, Heganovic L, Fleary K, Shaffer SN, Vairavan MS, Ferré-D’Amaré AR, Passalacqua LFM, Abdelsayed MM. The RNA thermometer motif ROSE-G regulates ABC transporter gene expression in bacteria. J Biol Chem. 2025 Dec 30. Epub ahead of print. 
• Hanrieder J, Sun R, Ellis SR, Pahnke J, Savas JN. Considerations for Spatial Omics, Metabolite Analyses, and Tissue-Harvesting Artifacts. J Neurochem. 2025 Dec. 
• Moreno-Estellés M, Campos-Rodríguez A, Viana R, Baños-Carrión L, Albuixech M, García-Gimeno MA, Gentry MS, Sanz P. A novel Lafora disease astrocytic cellular model to study polyglucosan accumulation and inflammation. Dis Model Mech. 2025 Dec 12. Epub ahead of print. 
• Schildgen O, Qiu J, Mietzsch M, Allander T, Jartti T, Schildgen V, Grimm D, Söderlund-Venermo M. Twenty years of human bocavirus research: from an unculturable virus of unclear pathogenicity to a culturable human pathogen and gene therapy vector candidate. Clin Microbiol Rev. 2025 Dec 11. Epub 2025 Oct 1. 
• Peng EQ, Nogueira MLC, Norton C, Brady LJ, Long JR. Backbone NMR resonance assignments for the C2 domain of the Streptococcus mutans adhesin P1. Biomol NMR Assign. 2025 Dec 13. 
• Huang M, Chen Y, Liang C, Narayan OP, Stallings C, Yu M, Traugot C, Li L, Li K, Vo Q, Wang H, Chou YT, Cech L, Parra D, Garzon L, Parsons D, Diaz E, Zhang C, Mackey C, Sussman H, Zmirska I, Chung M, Zhou C, Glynatsis G, Siemann DW, Licht JD, Li C, Kaye FJ, Xie M, Tan Y, Wu L, Bivona TG, Guan J, Tang X. Drug resistant cancer cells show increased nuclear mechanotransduction and mechanically targetable YAP-regulated vulnerability. Biomaterials. 2025 Dec 15. Epub ahead of print. 
• Pulido C, Gentry MS, Ryan TA. Neuromodulatory control of energy reserves in dopaminergic neurons. Proc Natl Acad Sci U S A. 2025 Dec 16. Epub 2025 Dec 5. 
• Fu R, Yu W, Zhao R, Yang H, Cao B, Dai C, Qianjiang H, Xia Y, Wang L, Lu J, Zhou R, Shi A, Lou H, Zhang X, Luo H. The METTL3-YTHDC1 axis mediates architectural RNA m⁶A modification to modulate the integrity of chromatin TADs in MLLr + AML genome. Mol Cancer. 2025 Dec 22. Epub ahead of print. 
• Brewer MK, Donohue KJ, Singh PK, Raththagala M, Simmons ZR, Wayne JL, Li S, Viana R, Segvich DM, Contreras CJ, Cantrell AR, Sanz P, Sun RC, Vander Kooi CW, Roach PJ, DePaoli-Roach A, Gentry MS. The biochemical dynamics of the glycogen phosphatase laforin directly impact brain metabolism. J Biol Chem. 2025 Dec 22. Epub ahead of print. 

November

• Shiraishi DH, Saha S, Adanyeguh IM, Cocozza S, Corben LA, Deistung A, Delatycki MB, Dogan I, Gaetz W, Georgiou-Karistianis N,Graf S, Grisoli M, Henry PG, Jarola GM, Joers JM, Langkammer C, Lenglet C, Li J, Lobo CC, Lock EF, Lynch DR, Mareci TH, MartinezARM, Monti S, Nigri A, Pandolfo M, Reetz K, Roberts TP, Romanzetti S, Rudko DA, Scaravilli A, Schulz JB, Subramony SH, Timmann D,França MC, Harding IH, Rezende TJR; TRACK-FA Neuroimaging Consortium. Automated Deep Learning-based Segmentation of theDentate Nucleus Using Quantitative Susceptibility Mapping MRI. Radiology: Artificial Intelligence. 2025 Nov.
• Pala N, Ladu F, Szlasa W, Cadoni R, Lomelino C, Mahon BP, Gulkis M, McKenna R, Dessì A, Dallocchio R, Demelas A, Carcelli M,Rogolino D, Crosio C, Iaccarino C, Kulbacka J, Vullo D, Carta F, Supuran CT, Sechi M. Design, anticancer activity, and mechanisticevaluation of a novel class of selective human carbonic anhydrase IX inhibitors featuring a trifluorodihydroxypropanonepharmacophore. European Journal of Medicinal Chemistry. 2025 Nov 15. Epub 2025 Aug 5.
• Muccioli L, Tappatà M, Farolfi A, Singh PK, Pasini E, Mazzone S, Esposito E, Motta L, D’Agati OM, Angeloni S, Caravelli A, Cancellerini C, Minardi R, Pizzi E, Carelli V, Tonon C, Fiori J, Gentry MS, Vignatelli L, Michelucci R, Bisulli F; DEFEAT-LD study group. New therapeutic strategies for Lafora disease: Evaluation of the safety, efficacy, pharmacokinetics and metabolomic profile of intravenous VAL-1221 treatment. Neurotherapeutics. 2025 Nov 30. Epub ahead of print. 
• Wang Y, Guo Y, Tan AC, Zhao L, Shi X, Chen Y, Sun RC, Liu M, Su J, George TJ, Bian J, Song Q. A real-world cohort study of immune-related adverse events in patients receiving immune checkpoint inhibitors. npj Precision Oncology. 2025 Nov 11. 
• Prasad R, Adu-Rutledge Y, Ziani B, Floyd JL, Ready EL, Paul S, Sheini F, Sharma R, Rosencrans RF, Li Calzi S, Sielski MS, Medawar NG, Dutta R, Johnson EB, Qi X, Bansal M, Lamendella R, Wright JR, Verma SK, Boulton ME, Stevens BR, Vander Kooi CW, Sun RC, Oudit GY, Li Q, Grant MB. Indole-3-propionic acid links gut dysfunction to diabetic retinopathy: a biomarker and novel therapeutic approach. Gut. 2025 Nov 5.  Epub ahead of print. 
• Hsi-Bell J, Mietzsch M, McKenna R. The amazing AAV capsids: Into the structure-verse. Mol Ther Methods Clin Dev. 2025 Nov 10. 
• Ribas RA, Paolasso FB, Ryan AM, Sanchez MR, Soto CM, Caffee SI, Larson RC, Allison DB, Gentry MS, Sun RC, Kooi CWV. Spatial Molecular Imaging of the Glycome Using Mass Spectrometry. J Vis Exp. 2025 Nov 28. 
• Brown ME, Barra JM, Pina MR, Proia J, Brusko TM, Russ HA. Human stem cell-derived β cells expressing an optimized CD155 reduce cytotoxic immune cell function for application in type 1 diabetes. Science Advances. 2025 Nov 7. Epub 2025 Nov 7. 

October

• Williams MI, Donohue KJ, Sanz P, Messahel S, Serratosa JM, Duran J, Michelucci R, Muccioli L, Delgado-Escueta A, Nguyen VV, MinassianBA, Gentry MS. The 9th annual Lafora science symposium: a rare epilepsy community makes progress towards clinical readiness.Epilepsy & Behavior. 2025 Oct. Epub 2025 Aug 27.
• Schildgen O, Qiu J, Mietzsch M, Allander T, Jartti T, Schildgen V, Grimm D, Söderlund-Venermo M. Twenty years of human bocavirusresearch: from an unculturable virus of unclear pathogenicity to a culturable human pathogen and gene therapy vector candidate.Clinical Microbiology Reviews. 2025 Oct 1. Epub ahead of print.
• Fusco AF, Rana S, Macintyre MM, Gonzalez IA, Ribas RA, Sun RC, Fuller DD. Acute Administration of Ampakine CX1739 afterCervical Spinal Cord Injury. Journal of Neurotrauma. 2025 Oct 6. Epub ahead of print.
• Michel KA, Harlan CJ, Walker CM, Merritt ME, Chen Y, Lai SY, Bankson JA. Pharmacokinetic modeling strategies for dynamichyperpolarized urea imaging. Magnetic Resonance in Medicine. 2025 Oct 12. Epub ahead of print.​
• Kotecha P, Donahoo WT, Sharma A, Singh Ospina N, Sun R, Yang C, Bian J, Guo J. Preoperative GLP-1 RA Use and PostoperativeRespiratory Complications in Patients Undergoing Elective Surgeries: A Target Trial Emulation Study. American Journal ofRespiratory and Critical Care Medicine. 2025 Oct 10. Epub ahead of print.
• Kim HG, Gauthier ML, Higgs A, Hernandez DA, Zhou M, Brant JO, Bacher RL, Darden DB, Wallet SM, Mathews CE, Moldawer LL, Efron PA, Kladde MP, Maile R. Chromatin Remodeling and Transcriptional Silencing Define the Dynamic Innate Immune Response of Tissue Resident Macrophages After Burn Injury. Shock. 2025 Oct 22. Epub ahead of print
• Smith LM, Lin YT, Mertens CS, Zabalawi ML, Long DL, Yoza BK, Cox AO, Prentice BM, Stacpoole PW, McCall CE. Pyruvate Dehydrogenase Complex Stimulation with Dichloroacetate May Improve Septic Cardiac Dysfunction. Shock. 2025 Oct 31. Epub ahead of print. 

September

• ​Nguyen A, Li T, Traugot C, Paulsen K, Nelson TS, Xie M, Ma Z. Essential function of the integrator complex in Kaposi’s sarcoma-associatedherpesvirus lytic replication. Journal of Virology. 2025 Sep 23. Epub 2025 Aug 13.​
• Nelson A, Mietzsch M, Hsi J, Eby J, Chipman P, McKenna R. Structural and Functional Characterization of Porcine Adeno-AssociatedViruses. Viruses. 2025 Sep 18.
• Siddique MS, Anand S, Gauthier ML, Brant JO, Kladde MP, Bhandari RK, Daigneault BW. Tributyltin chloride alters the structural, genomic,and epigenomic integrity of postejaculatory mammalian sperm. Epigenetics. 2025 Dec. Epub 2025 Sep 15.
• Fuller DD, Rana S, Thakre PP, Benevides ES, Pope MK, Todd AG, Jensen VN, Vaught L, Cloutier DA, Ribas RA, Larson RC, Gentry MS, SunRC, Chandran V, Corti M, Falk DJ, Byrne BJ. Neonatal systemic gene therapy restores cardiorespiratory function in a rat model of Pompedisease. Molecular Therapy. 2025 Sep 3. Epub 2025 Jun 14.
• Smith ED, Torrellas J, McKenna R, Vo Q, Mietzsch M, Borchelt DR, Prokop S, Chakrabarty P. Acetylation Mimetic and Null Mutations Withinthe Filament Core of P301L Tau Have Varied Effects on Susceptibility to Seeding and Aggregation. Journal of Neurochemistry. 2025 Sep.
• Lu Y, Oshins R, Maptue NR, Shen Q, Khemtong C, Cusi K, Brantly M, Khodayari N. Pioglitazone Reduces Hepatic Alpha-1 Antitrypsin Accumulation Through Autophagy and AMPK Activation in Alpha-1 Antitrypsin Deficient Mice. The American Journal of Physiology-Gastrointestinal and Liver Physiology. 2025 Sep 29. Epub ahead of print.
• Smith JA, Bloss DT, Williams MD, Posgai AL, Brusko TM, Atkinson MA, Wasserfall CH, Brusko MA. Protocol for processing and analyzing multiplexed images improves lymphatic cell identification and spatial architecture in human tissue. STAR Protocols. 2025 Sep 19. Epub 2025 Jul 25.

August

• Huang X, Zhang M, Pearce AD, Gibbons MD, Jin D, Li L, Hu D, Liu R, Yu M, Tan M, Chang J, Dong J, Xie M, Zhang W, Wu L, Flores C, BungertJ, Brusko TM, Lu J. Epithelial-Mesenchymal Transition Activates YAP to Drive Malignant Progression and Immune Evasion. Cancers(Basel). 2025 Aug 25.
• Busuttil K, Pittman N, Zachary J, Halder S, Geilen L, Singh A, Misseldine A, Kaplonek P, Chipman P, Heimburg-Molinaro J, Seeberger PH,Mietzsch M, Bennett AD, McKenna R. Mapping the sialic acid-binding sites of LuIII and H-1 parvovirus. Journal of Virology. 2025 Aug 19.Epub 2025 Jul 24.
• Wang H, Chen X, Dai Y, Pidathala S, Niu Y, Zhao C, Li S, Wang L, Lee CH. Structure and activation mechanism of human sweet taste receptor. Cell Research. 2025 Aug 4. Epub ahead of print.
• Shiraishi DH, Saha S, Adanyeguh IM, Cocozza S, Corben LA, Deistung A, Delatycki MB, Dogan I, Gaetz W, Georgiou-Karistianis N, Graf S, Grisoli M, Henry PG, Jarola GM, Joers JM, Langkammer C, Lenglet C, Li J, Lobo CC, Lock EF, Lynch DR, Mareci TH, Martinez ARM, Monti S, Nigri A, Pandolfo M, Reetz K, Roberts TP, Romanzetti S, Rudko DA, Scaravilli A, Schulz JB, Subramony SH, Timmann D, França MC Jr, Harding IH, Rezende TJR; TRACK-FA Neuroimaging Consortium. Automated Deep Learning-based Segmentation of the Dentate Nucleus Using Quantitative Susceptibility Mapping MRI. Radiology: Artificial Intelligence. 2025 Aug 6:e240478. Epub ahead of print.
• Pala N, Ladu F, Szlasa W, Cadoni R, Lomelino C, Mahon BP, Gulkis M, McKenna R, Dessì A, Dallocchio R, Demelas A, Carcelli M, Rogolino D, Crosio C, Iaccarino C, Kulbacka J, Vullo D, Carta F, Supuran CT, Sechi M. Design, anticancer activity, and mechanistic evaluation of a novel class of selective human carbonic anhydrase IX inhibitors featuring a trifluorodihydroxypropanone pharmacophore. European Journal of Medicinal Chemistry. 2025 Aug 5;298:118043. Epub ahead of print.

July

• Hsi J, Mietzsch M, Patney M, Chen S, Sawh-Gopal A, Chipman P, McKenna R. Birds of a feather flock together: structural characterization of red-crowned crane and turkey aveparvoviruses. Journal of Virology. 2025 Jul 22;99(7):e0011025. Epub 2025 Jul 3.
• Porter JM, Hulce KR, Oswald MS, Busuttil K, Emmanuel SN, Bennett A, McKenna R, Smith JG. Mechanisms of AAV neutralization by human alpha-defensins. PLOS Pathogens. 2025 Jul 18;21(7):e1013283.
• Busuttil K, Pittman N, Zachary J, Halder S, Geilen L, Singh A, Misseldine A, Kaplonek P, Chipman P, Heimburg-Molinaro J, Seeberger PH, Mietzsch M, Bennett AD, McKenna R. Mapping the sialic acid-binding sites of LuIII and H-1 parvovirus. Journal of Virology. 2025 Jul 24:e0029725. Epub ahead of print.
• Smith JA, Bloss DT, Williams MD, Posgai AL, Brusko TM, Atkinson MA, Wasserfall CH, Brusko MA. Protocol for processing and analyzing multiplexed images improves lymphatic cell identification and spatial architecture in human tissue. STAR Protocols. 2025 Jul 25;6(3):103976. Epub ahead of print.

June

• Fuller DD, Rana S, Thakre P, Benevides E, Pope M, Todd AG, Jensen VN, Vaught L, Cloutier D, Ribas RA, Larson RC, Gentry MS, Sun RC, Chandran V, Corti M, Falk DJ, Byrne BJ. Neonatal systemic gene therapy restores cardiorespiratory function in a rat model of Pompe disease. Molecular Therapy. 2025 Jun 14.
• Li T, Li L, Hiers NM, Sheng P, Wang Y, Traugot CM, Effinger-Morris JF, Akaphan P, Liu Y, Bian J, Fujii K, Xie M. Translation suppresses exogenous target RNA-mediated microRNA decay. Nature Communications. 2025 Jun 6.
• Tripathi A, Donkin RW, Miracle JS, Murphy RD, Gentry MS, Patwardhan A, Sinai AP. Dynamics of amylopectin granule accumulation during the course of chronic Toxoplasma infection is linked to intra-cyst bradyzoite replication. mSphere. 2025 Jun 10.
• Shukla S, Kanumuambidi JT, Rosales RR, Venkatesh A, Al-Toubat M, Mietzsch M, McKenna R, Balaji KC. Cyclin-dependent kinase 12 influences protein kinase D1 kinase activity. Biochemical and Biophysical Research Communications. 2025 Sep 1;777:152221. Epub 2025 Jun 19.
• Paulsen K, Chan R, Gay L, Ma Z. KSHV miRNAs target STING to evade innate immunity and facilitate KSHV lytic reactivation from latency. Cell Reports. 2025 Jun 24;44(6):115741. Epub 2025 May 24.

May

• Clarke HA, Ma X, Shedlock CJ, Medina T, Hawkinson TR, Wu L, Ribas RA, Keohane S, Ravi S, Bizon JL, Burke SN, Abisambra JF, Merritt ME, Prentice BM, Vander Kooi CW, Gentry MS, Chen L, Sun RC. Spatial mapping of the brain metabolome lipidome and glycome. Nature Communications. 2025 May 12.
• Kim JK, Lim SW, Jeong H, Lee C, Kim S, Son DW, Kumar R, Andring JT, Lomelino C, Wierman JL, Cohen AE, Shin TJ, Ghim CM, McKenna R, Jo BH, Min D, Choi JM, Kim CU. Fast product release requires active-site water dynamics in carbonic anhydrase. Nature Communications. 2025 May 12.
• Golden GJ, Wu VH, Hamilton JT, Amses KR, Shapiro MR, Sada Japp A, Liu C, Pampena MB, Kuri-Cervantes L, Knox JJ, Gardner JS; HPAP Consortium; Atkinson MA, Brusko TM, Luning Prak ET, Kaestner KH, Naji A, Betts MR. Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset. Nature Communications. 2025 May 18
• Meng W, Inampudi R, Zhang X, Xu J, Huang Y, Xie M, Bian J, Yin R. An Interpretable Population Graph Network to Identify Rapid Progression of Alzheimer’s Disease Using UK Biobank. AMIA Annual Symposium Proceedings. 2025 May 22.
• Radhakrishnan M, Balu KE, Karthik L, Nagampalli RSK, Nadendla EK, Krishnasamy G. Exploring the Antibiotic Potential of a Serine Protease from Solanum trilobatum Against Staphylococcus aureus Biofilms. Infectious Disease Reports. 2025 May 7.
• Rafikov R, Thompson DM, Rafikova O, Camp SM, Ribas RA, Sun RC, Gentry MS, Casanova NG, Garcia JGN. Predictive modeling of ARDS mortality integrating biomarker/cytokine, clinical and metabolomic data. Translational Research. 2025 May 24.
• Rushin A, Shaikh A, Hardin C, Deleyrolle LP, Merritt ME. Metabolic flux analysis of glioblastoma neural stem cells reveals distinctive metabolic phenotypes in ketogenic conditions. Scientific Reports. 2025 May 28.
• Stone D, Mietzsch M, Ronzitti G. Advancing AAV technology: From capsid design to scalable manufacturing. Molecular Therapy Methods & Clinical Development. 2025 May 7.
• Weeks-Pollenz SJ, Petrides MJ, Padgett-Pagliai KA, Davis R, Harris KK, Bloom LB. The YoaA-χ helicase modulates the dynamics of single-stranded DNA binding protein on DNA. Nature Communications. 2025 May 29.

April

• Mietzsch M, Hsi J, Nelson AR, Khandekar N, Huang AM, Smith NJ, Zachary J, Potts L, Farrar MA, Chipman P, Ghanem M, Alexander IE, Logan GJ, Huiskonen JT, McKenna R. Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts. Nature Communications. 2025 Apr 19.
• Lin J, He R, Qu Z, Dong J, Krabill AD, Wu L, Bai Y, Conroy LR, Bruntz RC, Miao Y, Jassim BA, Babalola B, Nguele Meke FGB, Sun R, Gentry MS, Zhang ZY. Discovery and Evaluation of Active Site-Directed, Potent, and Selective Sulfophenyl Acetic Amide-Based Inhibitors for the Laforin Phosphatase. Journal of Medicinal Chemistry. 2025 Apr 16. Epub ahead of print.
• Cantrell AR, Hawkinson TR, Juras JA, Webb MB, Medina T, Ribas RA, Collins J, Bunnell AA, Young LEA, Markussen KH, Andres DA, Long JR, Vander Kooi CW, Smith BN, Sun RC, Gentry MS. Protocol for high-power, brain-focused microwave fixation to define rodent metabolism. STAR Protocols. 2025 Apr 25.

March

• Georgiou-Karistianis N, Corben LA, Lock EF, Bujalka H, Adanyeguh I, Corti M, Deelchand DK, Delatycki MB, Dogan I, Farmer J, França MC Jr, Gabay AS, Gaetz W, Harding IH, Joers J, Lax MA, Li J, Lynch DR, Mareci TH, Martinez ARM, Pandolfo M, Papoutsi M, Parker RG, Reetz K, Rezende TJR, Roberts TP, Romanzetti S, Rudko DA, Saha S, Schulz JB, Subramony SH, Supramaniam VG, Lenglet C, Henry PG. Neuroimaging Biomarkers for Friedreich Ataxia: A Cross-Sectional Analysis of the TRACK-FA Study. Annals of Neurology. 2025 Mar 22. Epub ahead of print.
• Ma X, Shedlock CJ, Medina T, Ribas RA, Clarke HA, Hawkinson TR, Dande PK, Golamari HKR, Wu L, Ziani BE, Burke SN, Merritt ME, Vander Kooi CW, Gentry MS, Yadav NN, Chen L, Sun RC. AI-driven framework to map the brain metabolome in three dimensions. Nature Metabolism. 2025 Mar 18. Epub ahead of print.
• Giese APJ, Parker A, Rehman S, Brown SDM, Riazuddin S, Kooi CWV, Bowl MR, Ahmed ZM. CIB2 function is distinct from Whirlin in the development of cochlear stereocilia staircase pattern. Disease Models & Mechanisms. 2025 Mar 14. Epub ahead of print.
• Clarke HA, Hawkinson TR, Shedlock CJ, Medina T, Ribas RA, Wu L, Liu Z, Ma X, Xia Y, Huang Y, He X, Chang JE, Young LEA, Juras JA, Buoncristiani MD, James AN, Rushin A, Merritt ME, Mestas A, Lamb JF, Manauis EC, Austin GL, Chen L, Singh PK, Bian J, Vander Kooi CW, Evers BM, Brainson CF, Allison DB, Gentry MS, Sun RC. Glycogen drives tumour initiation and progression in lung adenocarcinoma. Nature Metabolism. 2025 Mar 11. Epub ahead of print.
• *Chang MC, Malut VR, Mahar R, Rushin A, McLeod MA, Pierre GL, Malut IR, Staklinski SJ, Glanz ME, Ragavan M, Sharma G, Madheswaran M, Badar A, Rao AD, Law BK, Kilberg MS, Collins JHP, Kodibagkar VD, Bankson JA, DeBerardinis RJ, Merritt ME. Assessing cancer therapeutic efficacy in vivo using [²H₇]glucose deuterium metabolic imaging. Science Advances. 2025 Mar 28. Epub 2025 Mar 26.
• Nar R, Gibbons MD, Perez L, Strouboulis J, Qian Z, Bungert J. TFII-I/GTF2I regulates globin gene expression and stress response in erythroid cells. Journal of Biological Chemistry. 2025 Mar. Epub 2025 Jan 24.

February

• Gliwa K, Hull J, Kansol A, Zembruski V, Lakshmanan R, Mietzsch M, Chipman P, Bennett A, McKenna R. Biophysical and structural insights into AAV genome ejection. Journal of Virology. 2025 Feb 5. Epub ahead of print. 
• Zhu B, Pitts MG, Buoncristiani MD, Bryant LT, Lopez-Nunez O, Gurria JP, Shedlock C, Ribas R, Keohane S, Liu J, Wang C, Gentry MS, Shelman NR, Allison DB, Evers BM, Sun RC, Rellinger EJ. GDP-mannose 4,6-dehydratase is a key driver of MYCN-amplified neuroblastoma core fucosylation and tumorigenesis. Oncogene. 2025 Feb 16. Epub ahead of print.
• Yu F, Zheng S, Yu C, Gao S, Shen Z, Nar R, Liu Z, Huang S, Wu L, Gu T, Qian Z. KRAS mutants confer platinum resistance by regulating ALKBH5 posttranslational modifications in lung cancer. J Clin Invest. 2025 Feb 4.
• Mietzsch M, Bennett A, McKenna R. Structural Capsidomics of Single-Stranded DNA Viruses. Viruses. 2025 Feb 27.

January

• Nar R, Gibbons MD, Perez L, Strouboulis J, Qian Z, Bungert J. TFII-I/GTF2I regulates globin gene expression and stress response in erythroid cells. Journal of Biological Chemistry. 2025 Jan 24. Epub ahead of print. 
• Bohsali AA, Gullett JM, FitzGerald DB, Mareci T, Crosson B, White K, Nadeau SE. Neural connectivity underlying core language functions. Brain and Language. 2025 Jan 23. Epub ahead of print. 
• Jabbari K, Mietzsch M, Hsi J, Chipman P, Qiu J, McKenna R. The Structural, Biophysical, and Antigenic Characterization of the Goose Parvovirus Capsid. Microorganisms. 2025 Jan 3. 
• Rezende TJR, Petit E, Park YW, Tezenas du Montcel S, Joers JM, DuBois JM, Moore Arnold H, Povazan M, Banan G, Valabregue R, Ehses P, Faber J, Coupé P, Onyike CU, Barker PB, Schmahmann JD, Ratai E-M, Subramony SH, Mareci TH, Bushara KO, Paulson H, Klockgether T, Durr A, Ashizawa T, Lenglet C, Öz G, Consortium R. Sensitivity of Advanced Magnetic Resonance Imaging to Progression over Six Months in Early Spinocerebellar Ataxia. Movement Disorders 2024. 

2024

December

• Park SH, Fadhul T, Conroy LR, Clarke HA, Sun RC, Wallenius K, Boucher J, O’Mahony G, Boianelli A, Persson M, Jung S, Jang C, Loria AS, Martinez GJ, Kipp ZA, Bates EA, Hinds TD Jr, Divanovic S, Softic S. Knockdown of ketohexokinase versus inhibition of its kinase activity exert divergent effects on fructose metabolism. JCI Insight. 2024 Dec 6. 
• Nogueira MLC, Lakshmanan R, Rivière G, Mietzsch M, Bennett A, McKenna R, Long JR. Backbone NMR resonance assignments for the VP1u N-terminal receptor-binding domain of the human parvovirus pathogen B19. Biomolecular NMR Assignments. 2024 Dec. Epub 2024 Jun 21. 

November

• Bennett A, Hull JA, Mietzsch M, Bhattacharya N, Chipman P, McKenna R. Maize Streak Virus: Single and Gemini Capsid Architecture. Viruses. 2024 Nov 29. 
• Mietzsch M, Kamat M, Basso K, Chipman P, Huiskonen JT, McKenna R. Structural characterization and epitope mapping of the AAVX affinity purification ligand. Molecular Therapy Methods & Clinical Development. 2024 Nov 12.  
• Combs JE, Murray AB, Lomelino CL, Mboge MY, Mietzsch M, Horenstein NA, Frost SC, McKenna R, Becker HM. Disruption of the Physical Interaction Between Carbonic Anhydrase IX and the Monocarboxylate Transporter 4 Impacts Lactate Transport in Breast Cancer Cells. International Journal of Molecular Sciences. 2024 Nov 8. 
• Yu H, Nagi SS, Usoskin D, Hu Y, Kupari J, Bouchatta O, Yan H, Cranfill SL, Gautam M, Su Y, Lu Y, Wymer J, Glanz M, Albrecht P, Song H, Ming GL, Prouty S, Seykora J, Wu H, Ma M, Marshall A, Rice FL, Li M, Olausson H, Ernfors P, Luo W. Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation. Nature Neuroscience. 2024 Nov 4. Epub ahead of print.
• Bibi S, Minsavage GV Jr, Figueiredo J, Timilsina S, Margin K, Quay J, Bendure H, Ryerson E, Calloway C, Andring J, Subedi A, McKenna R, Gulig P, Goss EM, Hurlbert JC, Jones JB. Interspecies Expression of an EF-HAND CALCIUM-BINDING PROTEIN in Xanthomonas perforans Leads to Reduced Virulence and Decreased Immune Evasion in Tomato Plants. Molecular Plant-Microbe Interactions. 2024 Nov. 

October

• Ni W, Yu M, Yang R, Li JW, Zhou X, Calbay O, Pi L, Lu J, Huang S, Wu L. The YAP1-MAML2 fusion drives tumorigenesis and sustains tumor growth. Molecular Therapy Oncology. 2024 Oct 28. 
• Costello HM, Eikenberry SA, Cheng KY, Broderick B, Joshi AS, Scott GR, McKee A, Mendez VM, Douma LG, Crislip GR, Gumz ML. Sex differences in the adrenal circadian clock: A role for BMAL1 in the regulation of urinary aldosterone excretion and renal electrolyte balance in mice. American Journal of Physiology-Renal Physiology. 2024 Oct 24. Epub ahead of print. 
• Wang B, Rocca JR, Hoshika S, Chen C, Yang Z, Esmaeeli R, Wang J, Pan X, Lu J, Wang KK, Cao YC, Tan W, Benner SA. A folding motif formed with an expanded genetic alphabet. Nature Chemistry. 2024 Oct. Epub 2024 Jun 10. 
• Shukla S, Osumi T, Al-Toubat M, Serrano S, Singh PK, Mietzsch M, McKenna R, Chardon-Robles J, Krishnan S, Balaji KC. Protein kinase D1 mitigation against etoposide induced DNA damage in prostate cancer is associated with increased α-Catenin. Prostate. 2024 Oct 20. Epub ahead of print. 
• Sheng Y, Abreu A, Markovich Z, Ebea P, Davis L, Park E, Sheng P, Xie M, Han SM, Xiao R. A mitochondrial unfolded protein response-independent role of DVE-1 in longevity regulation. Cell Reports. 2024 Oct 16. Epub ahead of print. 

September

• Davé UP, Bungert J. Toward life without sickle cell disease. Molecular Therapy. 2024 Sep 17. Epub ahead of print. 
• Colpaert M, Singh PK, Donohue KJ, Pires NT, Fuller DD, Corti M, Byrne BJ, Sun RC, Vander Kooi CW, Gentry MS. Neurological glycogen storage diseases and emerging therapeutics. Neurotherapeutics. 2024 Sep 13. Epub ahead of print. 
• Zhou C, Sun C, Zhou W, Tian T, Schultz DC, Wu T, Yu M, Wu L, Pi L, Li Chenglong. Development of Novel Indole-Based Covalent Inhibitors of TEAD as Potential Antiliver Cancer Agents. Journal of Medicinal Chemistry. 2024 Sep 13. Epub ahead of print. 

August

• McLeod M, Chang MC, Rushin A, Ragavan M, Mahar R, Sharma G, Badar A, Giacalone A, Glanz ME, Malut VR, Graham D, Sunny NE, Bankson JA, Cusi K, Merritt ME. Detecting altered hepatic lipid oxidation by MRI in an animal model of MASLD. Cell Reports Medicine. 2024 Aug 29. Epub ahead of print. 
• Veronese BHS, Nguyen A, Patel K, Paulsen K, Ma Z. ORF48 is required for optimal lytic replication of Kaposi’s sarcoma-associated herpesvirus. PLoS Pathogens. 2024 Aug 26. Epub ahead of print. 
• Zhou Y, Sheng P, Li J, Li Y, Xie M, Green AA. Conditional RNA interference in mammalian cells via RNA transactivation. Nature Communications. 2024 Aug 10. 
• Gulkis M, Luo M, Chipman P, Mietzsch M, Söderlund-Venermo M, Bennett A, McKenna R. Structural Characterization of Human Bufavirus 1: Receptor Binding and Endosomal pH-Induced Changes. Viruses. 2024 Aug 6. 
• Painter CD, Sankaranarayanan NV, Nagarajan B, Mandel Clausen T, West AMV, Setiawan NJ, Park J, Porell RN, Bartels PL, Sandoval DR, Vasquez GJ, Chute JP, Godula K, Vander Kooi CW, Gordts PLSM, Corbett KD, Termini CM, Desai UR, Esko JD. Alteration of Neuropilin-1 and Heparan Sulfate Interaction Impairs Murine B16 Tumor Growth. American Chemical Society Chemical Biology Journal. 2024 Aug 4. Epub ahead of print. 
• Bibi S, Minsavage GV, Figueiredo J, Timilsina S, Margin K, Quay J, Bendure H, Ryerson E, Calloway C, Andring J, Subedi A, McKenna R, Gulig P, Goss EM, Hurlbert JC, Jones JB. Inter-species expression of an EF-HAND CALCIUM BINDING PROTEIN in Xanthomonas perforans leads to reduced virulence and decreased immune evasion in tomato plants. Molecular Plant-Microbe Interactions. 2024 Aug 2. Epub ahead of print. 

July

• Yin R, Zhao H, Li L, Yang Q, Zeng M, Yang C, Bian J, Xie M. Gra-CRC-miRTar: The pre-trained nucleotide-to-graph neural networks to identify potential miRNA targets in colorectal cancer. Computational and Structural Biotechnology Journal. 2024 Jul 18. 
• Stacpoole PW, Dirain CO. The pyruvate dehydrogenase complex at the epigenetic crossroads of acetylation and lactylation. Molecular Genetics and Metabolism. 2024 Jul 16. Epub ahead of print. 
• Scott FJ, Dubroca T, Schurko RW, Hill S, Long JR, Mentink-Vigier F. Characterization of dielectric properties and their impact on MAS-DNP NMR applications. Journal of Magnetic Resonance. 2024 Jul 15. Epub ahead of print. 
• Li X, Gao L, Wang B, Hu J, Yu Y, Gu B, Xiang L, Li X, Li H, Zhang T, Wang Y, Ma C, Dong J, Lu J, Lucas A, Chen H. FXa-mediated PAR-2 promotes the efficacy of immunotherapy for hepatocellular carcinoma through immune escape and anoikis resistance by inducing PD-L1 transcription. Journal for ImmunoTherapy of Cancer. 2024 Jul 25. 
• Mietzsch M, Kailasan S, Bennett A, Chipman P, Fane B, Huiskonen JT, Clarke IN, McKenna R. The Structure of Spiroplasma Virus 4: Exploring the Capsid Diversity of the Microviridae. Viruses. 2024 Jul 9. 
• Li Z, Lange M, Dixon SJ, Olzmann JA. Lipid Quality Control and Ferroptosis: From Concept to Mechanism. Annual Review of Biochemistry. 2024 Aug. Epub 2024 Jul 2. 

June

• Wang Y, Wang E, Anany M, Füllsack S, Huo YH, Dutta S, Ji B, Hoeppner LH, Kilari S, Misra S, Caulfield T, Vander Kooi CW, Wajant H, Mukhopadhyay D. The crosstalk between neuropilin-1 and tumor necrosis factor-α in endothelial cells. Frontiers in Cell and Developmental Biology. 2024 Jun 27. 
• Nogueira MLC, Lakshmanan R, Rivière G, Mietzsch M, Bennett A, McKenna R, Long JR. Backbone NMR resonance assignments for the VP1u N-terminal receptor-binding domain of the human parvovirus pathogen B19. Biomolecular NMR Assignments. 2024 Jun 21. Epub ahead of print. 
• Li L, Qin R, Liu Y, Tseng YS, Zhang W, Yu L, Mietzsch M, Zou X, Liu H, Lu G, Hu H, Mckenna R, Yang J, Wei Y, Agbandje-Mckenna M, Hu J, Yang L. Dissecting positive selection events and immunological drives during the evolution of adeno-associated virus lineages. PLoS Pathogens. 2024 Jun 17. 
• Wang B, Rocca JR, Hoshika S, Chen C, Yang Z, Esmaeeli R, Wang J, Pan X, Lu J, Wang KK, Cao YC, Tan W, Benner SA. A folding motif formed with an expanded genetic alphabet. Nature Chemistry. 2024 Jun 10. Epub ahead of print. 

May

• Brewer MK, Torres P, Ayala V, Portero-Otin M, Pamplona R, Andrés-Benito P, Ferrer I, Gentry MS, Guinovart JJ, Duran J. Glycogen accumulation modulates life span in a mouse model of amyotrophic lateral sclerosis. Journal of Neurochemistry. 2024 May.
• Markussen KH, Corti M, Byrne BJ, Vander Kooi CW, Sun RC, Gentry MS. The multifaceted roles of the brain glycogen. Journal of Neurochemistry. 2024 May.
• Jang SJ, Atyeo N, Mietzsch M, Chae MY, McKenna R, Toth Z, Papp B. Genome-Wide Transcriptional Roles of KSHV Viral Interferon Regulatory Factors in Oral Epithelial Cells. Viruses. 2024 May 25. 
• Liu Y, Kwok W, Yoon H, Ryu JC, Stevens P, Hawkinson TR, Shedlock CJ, Ribas RA, Medina T, Keohane SB, Scharre D, Bruschweiler-Li L, Bruschweiler R, Gaultier A, Obrietan K, Sun RC, Yoon SO. Imbalance in Glucose Metabolism Regulates the Transition of Microglia from Homeostasis to Disease-Associated Microglia Stage 1. Journal of Neuroscience. 2024 May 15.
• Taylor CE, Mendenhall LE, Sunshine MD, Wilson JN, Calulot CM, Sun RC, Johnson LA, Alilain WJ. Sex and APOE Genotype Influence Respiratory Function Under Hypoxic and Hypoxic-Hypercapnic Conditions. Journal of Neurophysiology. 2024 May 15.
• Goetz A, Cagmat J, Brusko M, Brusko TM, Rushin A, Merritt M, Garrett T, Morel L, Dixit P. A global view of T cell metabolism in systemic lupus erythematosus. Frontiers in Immunology. 2024 May 2.
• ​Barrios EL, Rincon JC, Willis M, Polcz VE, Leary JR, Darden DB, Balch JA, Larson SD, Loftus TJ, Mohr AM, Wallet S, Brusko MA, Balzano-Nogueira L, Cai G, Sharma A, Upchurch GR Jr, Kladde MP, Mathews CE, Maile R, Moldawer LL, Bacher R, Efron PA. TRANSCRIPTOMIC DIFFERENCES IN PERIPHERAL MONOCYTE POPULATIONS IN SEPTIC PATIENTS BASED ON OUTCOME. Shock. 2024 Aug 1. Epub 2024 May 2. 

April

• Zhou M, Riva A, Gauthier ML, Kladde MP, Ferl RJ, Paul AL. Single-molecule long-read methylation profiling reveals regional DNA methylation regulated by Elongator Complex Subunit 2 in Arabidopsis roots experiencing spaceflight. Biology Direct. 2024 Apr 30.​
• Cilenti L, Di Gregorio J, Mahar R, Liu F, Ambivero CT, Periasamy M, Merritt ME, Zervos AS. Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice. Frontiers in Molecular Biosciences. 2024 Apr 25.​
• Barrios EL, Leary JR, Darden DB, Rincon JC, Willis M, Polcz VE, Gillies GS, Munley JA, Dirain ML, Ungaro R, Nacionales DC, Gauthier ML, Larson SD, Morel L, Loftus TJ, Mohr AM, Maile R, Kladde MP, Mathews CE, Brusko MA, Brusko TM, Moldawer LL, Bacher R, Efron PA. The post-septic peripheral myeloid compartment reveals unexpected diversity in myeloid-derived suppressor cells. Frontiers in Immunology. 2024 Apr 24.​
• Wang B, Pan X, Teng IT, Li X, Kobeissy F, Wu ZY, Zhu J, Cai G, Yan H, Yan X, Liang M, Yu F, Lu J, Yang Z, Biondi E, Haskins W, Cao YC, Benner SA, Tan W, Wang KK. Functional Selection of Tau Oligomerization-Inhibiting Aptamers. Angewandte Chemie International Edition in English. 2024 Apr 24. Epub 2024 Mar 14.​
• Liu Y, Kwok W, Yoon H, Ryu JC, Stevens P, Hawkinson TR, Shedlock CJ, Ribas RA, Medina T, Keohane SB, Scharre D, Bruschweiler-Li L, Bruschweiler R, Gaultier A, Obrietan K, Sun RC, Yoon SO. Imbalance in glucose metabolism regulates the transition of microglia from homeostasis to Disease Associated Microglia stage 1. Journal of Neuroscience. 2024 Apr 16: Epub ahead of print.​

March

• Hiers NM, Li T, Traugot CM, Xie M. Target-directed microRNA degradation: Mechanisms, significance, and functional implications. Wiley Interdisciplinary Reviews: RNA. 2024 Mar-Apr;15​
• Zhao C. Limitations in membrane protein structure determination by lipid nanodiscs. Trends in Biochemical Sciences. 2024 Mar 26: Epub ahead of print.
• Yu F, Liu S, Zhu AC, He C, Qian Z. Protocol for detecting RBM33-binding sites in HEK293T cells using PAR-CLIP-seq. STAR Protocols. 2024 Mar 15; Epub 2024 Jan 31.
• Febo M, Mahar R, Rodriguez NA, Buraima J, Pompilus M, Pinto AM, Grudny MM, Bruijnzeel AW, Merritt ME. Age-related differences in affective behaviors in mice: possible role of prefrontal cortical-hippocampal functional connectivity and metabolomic profiles. Frontiers in Aging Neuroscience. 2024 Mar 8.​
• Hull JA, Lee C, Kim JK, Lim SW, Park J, Park S, Lee SJ, Park G, Eom I, Kim M, Hyun H, Combs JE, Andring JT, Lomelino C, Kim CU, McKenna R. XFEL structure of carbonic anhydrase II: a comparative study of XFEL, NMR, X-ray and neutron structures. Acta Crystallographica D Structural Biology. 2024 Mar 1; Epub 2024 Feb 27.​

February

• Wallace SM, Zhou L, Ma Q, Denslow ND, Bonzongo JJ, Gaillard JF. An XAS study of Hg(II) sorption to Al-based drinking water treatment residuals. Chemosphere. 2024 Feb; Epub 2023 Dec 13.
• Wang B, Pan X, Teng IT, Li X, Kobeissy F, Wu ZY, Zhu J, Cai G, Yan H, Yan X, Liang M, Yu F, Lu J, Yang Z, Biondi E, Haskins W, Cao YC, Benner SA, Tan W, Wang KK. Functional Selection of Tau Oligomerization-Inhibiting Aptamers. Angewandte Chemie International Edition English. 2024 Feb 26: Epub ahead of print.​
• Debnath J, Keshamasetthy D, Combs J, Leon K, Vullo D, Chatterjee A, McKenna R, Supuran CT. A comparative study of diaryl urea molecules with and without sulfonamide group on Carbonic anhydrase IX and XII inhibition and its consequence on breast cancer cells. Bioorganic Chemistry. 2024 Apr; Epub 2024 Feb 10.​
• Zafra-Puerta L, Colpaert M, Iglesias-Cabeza N, Burgos DF, Sánchez-Martín G, Gentry MS, Sánchez MP, Serratosa JM. Effect of intracerebroventricular administration of alglucosidase alfa in two mouse models of Lafora disease: Relevance for clinical practice. Epilepsy Research. 2024 Feb; Epub 2024 Feb 6.​

January

• Ullman JC, Mellem KT, Xi Y, Ramanan V, Merritt H, Choy R, Gujral T, Young LEA, Blake K, Tep S, Homburger JR, O’Regan A, Ganesh S, Wong P, Satterfield TF, Lin B, Situ E, Yu C, Espanol B, Sarwaikar R, Fastman N, Tzitzilonis C, Lee P, Reiton D, Morton V, Santiago P, Won W, Powers H, Cummings BB, Hoek M, Graham RR, Chandriani SJ, Bainer R, DePaoli-Roach AA, Roach PJ, Hurley TD, Sun RC, Gentry MS, Sinz C, Dick RA, Noonberg SB, Beattie DT, Morgans DJ Jr, Green EM. Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders. Science Translational Medicine. 2024 Jan 17. Epub 2024 Jan 17.
• Lakshmanan RV, Agbandje-McKenna M, McKenna R. Feasibility of Domain Segmentation of B19V VP1u Using Intein Technology for Structural Studies. Protein and Peptide Letters. 2024 Jan 12. Epub ahead of print.
• Aiyer S, Baldwin PR, Tan SM, Shan Z, Oh J, Mehrani A, Bowman ME, Louie G, Passos DO, Đorđević-Marquardt S, Mietzsch M, Hull JA, Hoshika S, Barad BA, Grotjahn DA, McKenna R, Agbandje-McKenna M, Benner SA, Noel JAP, Wang D, Tan YZ, Lyumkis D. Overcoming resolution attenuation during tilted cryo-EM data collection. Nature Communications. 2024 Jan 9.
• Photenhauer AL, Villafuerte-Vega RC, Cerqueira FM, Armbruster KM, Mareček F, Chen T, Wawrzak Z, Hopkins JB, Vander Kooi CW, Janeček Š, Ruotolo BT, Koropatkin NM. The Ruminococcus bromii amylosome protein Sas6 binds single and double helical α-glucan structures in starch. Nature Structural & Molecular Biology. 2024 Jan 4. Epub ahead of print.

2023

December

• Murray KO, Brant JO, Spradlin RA, Thome T, Laitano O, Ryan TE, Riva A, Kladde MP, Clanton TL. Exertional heat stroke causes long-term skeletal muscle epigenetic reprogramming, altered gene expression and impaired satellite cell function in mice. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2023 Dec 4. Epub ahead of print.

November

• Tanner JJ, Amin M, Dion C, Parvataneni HK, Mareci T, Price CC. Perioperative Extracellular Brain Free-Water Changes for Older Adults Electing Total Knee Arthroplasty with General versus Spinal Anesthesia: A Pilot Study. Journal of Alzheimer’s Disease. 2023.
• Li Z, Lange M, Dixon SJ, Olzmann JA. Lipid Quality Control and Ferroptosis: From Concept to Mechanism. Annual Review of Biochemistry. 2023 Nov 14. Epub ahead of print.

October

• Chang MC, Staklinski SJ, Merritt ME, Kilberg MS. A method for measurement of human asparagine synthetase (ASNS) activity and application to ASNS protein variants associated with ASNS deficiency. Biology Methods and Protocols. 2023 Oct 25.
• Peng EQ, Caldas Nogueira ML, Rivière G, Brady LJ, Long JR. Backbone NMR resonance assignments for the C terminal domain of the Streptococcus mutans adhesin P1. Biomolecular NMR Assignments. 2023 Oct 21. Epub ahead of print.
• Hasani S, Young LEA, Van Nort W, Banerjee M, Rivas DR, Kim J, Xiong X, Sun RC, Gentry MS, Sesaki H, Gao T. Inhibition of mitochondrial fission activates glycogen synthesis to support cell survival in colon cancer. Cell Death and Disease. 2023 Oct 10
• Wang Y, Traugot CM, Bubenik JL, Li T, Sheng P, Hiers NM, Fernandez P, Li L, Bian J, Swanson MS, Xie M. N⁶-methyladenosine in 7SK small nuclear RNA underlies RNA polymerase II transcription regulation. Molecular Cell. 2023 Oct 6
• Zelows MM, Cady C, Dharanipragada N, Mead AE, Kipp ZA, Bates EA, Varadharajan V, Banerjee R, Park SH, Shelman NR, Clarke HA, Hawkinson TR, Medina T, Sun RC, Lydic TA, Hinds TD Jr, Brown JM, Softic S, Graf GA, Helsley RN. Loss of carnitine palmitoyltransferase 1a reduces docosahexaenoic acid-containing phospholipids and drives sexually dimorphic liver disease in mice. Molecular Metabolism. 2023 Oct 4. Epub ahead of print.
• Leon-Astudillo C, Trivedi PD, Sun RC, Gentry MS, Fuller DD, Byrne BJ, Corti M. Current avenues of gene therapy in Pompe disease. Current Opinion in Neurology. 2023 Oct 1;36(5):464-473. Epub 2023 Jul 19. 

September

• Wu L, Wang F, Moncman CL, Pandey M, Clarke HA, Frazier HN, Young LEA, Gentry MS, Cai W, Thibault O, Sun RC, Andres DA. RIT1 regulation of CNS lipids RIT1 deficiency Alters cerebral lipid metabolism and reduces white matter tract oligodendrocytes and conduction velocities. Heliyon. 2023 Sep 23
• Stacpoole PW. Clinical Physiology and Pharmacology of GSTZ1/MAAI. Biochem Pharmacology. 2023 Sep 22. Epub ahead of print. 
• Crislip GR, Costello HM, Juffre A, Cheng KY, Lynch IJ, Johnston JG, Drucker CB, Bratanatawira P, Agarwal A, Mendez VM, Thelwell RS, Douma LG, Wingo CS, Alli AA, Scindia YM, Gumz ML. Male kidney-specific BMAL1 knockout mice are protected from Potassium-deficient, high salt diet-induced blood pressure increases. American Journal of Physiology-Renal Physiology. 2023 Sep 14. Epub ahead of print. 
• Hsi J, Mietzsch M, Chipman P, Afione S, Zeher A, Huang R, Chiorini J, McKenna R. Structural and antigenic characterization of the avian adeno-associated virus capsid. Journal of Virology. 2023 Sep 13. Epub ahead of print. 
• Donohue KJ, Fitzsimmons B, Bruntz RC, Markussen KH, Young LEA, Clarke HA, Coburn PT, Griffith LE, Sanders W, Klier J, Burke SN, Maurer AP, Minassian BA, Sun RC, Kordasiewisz HB, Gentry MS. Gys1 Antisense Therapy Prevents Disease-Driving Aggregates and Epileptiform Discharges in a Lafora Disease Mouse Model. Neurotherapeutics. 2023 Sep 12. Epub ahead of print. 
• Zhang Y, Lin D, Zheng Y, Chen Y, Yu M, Cui D, Huang M, Su X, Sun Y, Chen Y, Qian Z, Carlson KS, Wen R, Wang D. MiR-9-1 controls osteoblastic regulation of lymphopoiesis. Leukemia. 2023 Sep 5. Epub ahead of print. 
• Xia M, Anderson TA, Prantzalos ER, Hawkinson TR, Clarke HA, Keohane SB, Sun RC, Turner JR, Ortinski PI. Voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes. Neuropsychopharmacology. 2023 Sep 2. Epub ahead of print. 
• Pondrelli F, Minardi R, Muccioli L, Zenesini C, Vignatelli L, Licchetta L, Mostacci B, Tinuper P, Vander Kooi CW, Gentry MS, Bisulli F. Prognostic value of pathogenic variants in Lafora Disease: systematic review and meta-analysis of patient-level data. Orphanet Journal of Rare Diseases. 2023 Sep 2. 

August

• Dantas Machado AC, Ramos SF, Gauglitz JM, Fassler AM, Petras D, Aksenov AA, Kim UB, Lazarowicz M, Barnard Giustini A, Aryafar H, Vodkin I, Warren C, Dorrestein PC, Zarrinpar A, Zarrinpar A. Portosystemic shunt placement reveals blood signatures for the development of hepatic encephalopathy through mass spectrometry. Nature Communications. 2023 Aug 31 
• Velez M, Mietzsch M, Hsi J, Bell L, Chipman P, Fu X, McKenna R. Structural Characterization of Canine Minute Virus, Rat and Porcine Bocavirus. Viruses. 2023 Aug 24
• Kok CY, Tsurusaki S, Cabanes-Creus M, Igoor S, Rao R, Skelton R, Liao SHY, Ginn SL, Knight M, Scott S, Mietzsch M, Fitzsimmons R, Miller J, Mohamed TMA, McKenna R, Chong JJH, Hill AP, Hudson JE, Alexander IE, Lisowski L, Kizana E. Development of new adeno-associated virus capsid variants for targeted gene delivery to human cardiomyocytes. Molecular Therapy – Methods and Clinical Development. 2023 Aug 18. 
• Cai F, Bezwada D, Cai L, Mahar R, Wu Z, Chang MC, Pachnis P, Yang C, Kelekar S, Gu W, Brooks B, Ko B, Vu HS, Mathews TP, Zacharias LG, Martin-Sandoval M, Do D, Oaxaca KC, Jin ES, Margulis V, Malloy CR, Merritt ME, DeBerardinis RJ. Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples. Cell Metabolism. 2023 Aug 15: Epub ahead of print.  
• Markussen KH, Corti M, Byrne BJ, Vander Kooi CW, Sun RC, Gentry MS. The multifaceted roles of the brain glycogen. Journal of Neurochemistry. 2023 Aug 9. Epub ahead of print. 
• Huang M, Wang H, Mackey C, Chung MC, Guan J, Zheng G, Roy A, Xie M, Vulpe C, Tang X. YAP at the Crossroads of Biomechanics and Drug Resistance in Human Cancer. International Journal of Molecular Sciences. 2023 Aug 6. 
• Yu C, Sheng Y, Yu F, Ni H, Qiu A, Huang Y, Qian Z. Foxm1 haploinsufficiency drives clonal hematopoiesis and promotes a stress-related transition to hematologic malignancy in mice. Journal of Clinical Investigation. 2023 Aug 1. 

July

• Bennett A, Gargas J, Kansol A, Lewis J, Hsi J, Hull J, Mietzsch M, Tartaglia L, Muzyczka N, Bhattacharya N, Chipman P, Agbandje-McKenna M, McKenna R. Structural and Biophysical Analysis of Adeno-Associated Virus Serotype 2 Capsid Assembly Variants. Journal of Virology. 2023 Jul 27. Epub 2023 Jun 13. 
• Rushin A, McLeod MA, Ragavan M, Merritt ME. Observing exocrine pancreas metabolism using a novel pancreas perfusion technique in combination with hyperpolarized [1-¹³ C]pyruvate. Magnetic Resonance in Chemistry. 2023 Jul 22. Epub ahead of print. 
• Logan GJ, Mietzsch M, Khandekar N, D’Silva A, Anderson D, Mandwie M, Hsi J, Nelson AR, Chipman P, Jackson J, Schofield P, Christ D, Goodnow CC, Reed JH, Farrar MA, McKenna R, Alexander IE. Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy. Molecular Therapy. 2023 Jul 5 

June

• Yu F, Zhu AC, Liu S, Gao B, Wang Y, Khudaverdyan N, Yu C, Wu Q, Jiang Y, Song J, Jin L, He C, Qian Z. RBM33 is a unique m⁶A RNA-binding protein that regulates ALKBH5 demethylase activity and substrate selectivity. Molecular Cell. 2023 Jun 15 
• Yu F, Qian Z. Mechanisms for regulation of RAS palmitoylation and plasma membrane trafficking in hematopoietic malignancies. Journal of Clinical Investigation. 2023 Jun 15 
• Bennett A, Gargas J, Kansol A, Lewis J, Hsi J, Hull J, Mietzsch M, Tartaglia L, Muzyczka N, Bhattacharya N, Chipman P, Agbandje-McKenna M, McKenna R. Structural and Biophysical Analysis of Adeno-Associated Virus Serotype 2 Capsid Assembly Variants. Journal of Virology. 2023 Jun 13 
• Chen H, Yan C, Dhasarathy A, Kladde M, Bai L. Investigating pioneer factor activity and its coordination with chromatin remodelers using integrated synthetic oligo assay. STAR Protocols. 2023 Jun 7; Epub ahead of print. 
• Rey JA, Farid UM, Najjoum CM, Brown A, Magdoom KN, Mareci TH, Sarntinoranont M. Perivascular network segmentations derived from high-field MRI and their implications for perivascular and parenchymal mass transport in the rat brain. Scientific Reports. 2023 Jun 6 
• Liang C, Huang M, Tanaka M, Lightsey S, Temples M, Lepler SE, Sheng P, Mann WP, Widener AE, Siemann DW, Sharma B, Xie M, Dai Y, Phelps E, Zeng B, Tang X. Functional Interrogation of Ca²⁺ Signals in Human Cancer Cells In Vitro and Ex Vivo by Fluorescent Microscopy and Molecular Tools. Methods in Molecular Biology. 2023 

May

• Ellis JA, Hale MA, Cleary JD, Wang E, Andrew Berglund J. Alternative splicing outcomes across an RNA-binding protein concentration gradient. Journal of Molecular Biology. 2023 May 23. Epub ahead of print. 
• Huang L, Zhang J, Wei B, Chen S, Zhu S, Qi W, Pei X, Li L, Liu W, Wang Y, Xu X, Xie LG, Chen L. Small-molecule MHC-II inducers promote immune detection and anti-cancer immunity via editing cancer metabolism. Cell Chemical Biology. 2023 May 22. Epub ahead of print. 
• Mietzsch M, Qiu J, Almendral JM, Söderlund-Venermo M. Editorial: Parvoviruses: from basic research to biomedical and biotechnological applications. Frontiers in Microbiology. 2023 May 15. 
• Mietzsch M, Liu W, Ma K, Bennett A, Nelson AR, Gliwa K, Chipman P, Fu X, Bechler S, McKenna R, Viner R. Production and characterization of an AAV1-VP3-only capsid: An analytical benchmark standard. Molecular Therapy – Methods & Clinical Development. 2023 May 9 

April

• Guijarro MV, Kellish PC, Dib PE, Paciaroni NG, Nawab A, Andring J, Kulemina L, Borrero NV, Modenutti C, Feely M, Nasri E, Seifert RP, Luo X, Bennett RL, Shabashvili D, Licht JD, McKenna R, Roitberg A, Huigens Iii RW, Kaye FJ, Zajac-Kaye M. First-in-class multifunctional TYMS non-classical antifolate inhibitor with potent in vivo activity that prolongs survival. Journal of Clinical Investigation Insight. 2023 Apr 25. Epub ahead of print. 
• Chang MC, Staklinski SJ, Malut VR, Pierre GL, Kilberg MS, Merritt ME. Metabolomic Profiling of Asparagine Deprivation in Asparagine Synthetase Deficiency Patient-Derived Cells. Nutrients. 2023 Apr 18.​
• Chin Y, Gumilar KE, Li XG, Tjokroprawiro BA, Lu CH, Lu J, Zhou M, Sobol RW, Tan M. Targeting HSF1 for cancer treatment: mechanisms and inhibitor development. Theranostics. 2023 Apr 17.​
• Sheng P, Li L, Li T, Wang Y, Hiers NM, Mejia JS, Sanchez JS, Zhou L, Xie M. Screening of Drosophila microRNA-degradation sequences reveals Argonaute1 mRNA’s role in regulating miR-999. Nature Communications. 2023 Apr 13;14(1):2108. ​
• Gobin C, Inkabi S, Lattimore CC, Gu T, Menefee JN, Rodriguez M, Kates H, Fields C, Bian T, Silver N, Xing C, Yates C, Renne R, Xie M, Fredenburg KM. Investigating miR-9 as a mediator in laryngeal cancer health disparities. Frontiers in Oncology. 2023 Apr 4;13:1096882.
• Logan GJ, Mietzsch M, Khandekar N, D’Silva A, Anderson D, Mandwie M, Hsi J, Nelson AR, Chipman P, Jackson J, Schofield P, Christ D, Goodnow CC, Reed JH, Farrar MA, McKenna R, Alexander IE. Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy. Molecular Therapy. 2023 Apr 3:S1525-0016(23)00165-X.​

March

• Johnston JG, Welch AK, Cain BD, Sayeski PP, Gumz ML, Wingo CS. Aldosterone: Renal Action and Physiological Effects. Comprehensive Physiology. 2023 Mar 30;13(2):4409-4491.​
• Chen Z, Zhou K, Xue J, Small A, Xiao G, Nguyen LXT, Zhang Z, Prince E, Weng H, Huang H, Zhao Z, Qing Y, Shen C, Li W, Han L, Tan B, Su R, Qin H, Li Y, Wu D, Gu Z, Ngo VN, He X, Chao J, Leung K, Wang K, Dong L, Qin X, Cai Z, Sheng Y, Chen Y, Wu X, Zhang B, Shi Y, Marcucci G, Qian Z, Xu M, Müschen M, Chen J, Deng X. Phosphorylation stabilized TET1 acts as an oncoprotein and therapeutic target in B cell acute lymphoblastic leukemia. Science Translational Medicine. 2023 Mar 29 ​
• Zhang Z, Zhou K, Han L, Small A, Xue J, Huang H, Weng H, Su R, Tan B, Shen C, Li W, Zhao Z, Qing Y, Qin X, Wang K, Leung K, Boldin M, Chen CW, Ann D, Qian Z, Deng X, Chen J, Chen Z. RNA m⁶A reader YTHDF2 facilitates precursor miR-126 maturation to promote acute myeloid leukemia progression. Genes and Disease. 2023 Mar 28.  ​
• Kamson DO, Chinnasamy V, Grossman SA, Bettegowda C, Barker PB, Stacpoole PW, Oeltzschner G. In-vivo magnetic resonance spectroscopy of lactate as a non-invasive biomarker of dichloroacetate activity in cancer and non-cancer central nervous system disorders. Frontiers in Oncology 2023 Mar 17;13:1077461.​
• Porter JM, Oswald MS, Sharma A, Emmanuel S, Kansol A, Bennett A, McKenna R, Smith JG. A Single Surface-Exposed Amino Acid Determines Differential Neutralization of AAV1 and AAV6 by Human Alpha-Defensins. Journal of Virology. 2023 Mar 14: Epub ahead of print.​
• Combs LR, Combs J, McKenna R, Toth Z. Protein Degradation by Gammaherpesvirus RTAs: More Than Just Viral Transactivators. Viruses. 2023 Mar 11;15(3):730.​
• Frost CJ, Ramirez-Mata A, Khattri RB, Merritt ME, Frost SC. Effects of β-caryophyllene and oxygen availability on cholesterol and fatty acids in breast cancer cells. PLoS One. 2023 Mar 9​ ​
• Lee S, Devanney NA, Golden LR, Smith CT, Schwartz JL, Walsh AE, Clarke HA, Goulding DS, Allenger EJ, Morillo-Segovia G, Friday CM, Gorman AA, Hawkinson TR, MacLean SM, Williams HC, Sun RC, Morganti JM, Johnson LA. APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge. Cell Reports. 2023 Mar 3​
• Getu AA, Tigabu A, Zhou M, Lu J, Fodstad Ø, Tan M. New frontiers in immune checkpoint B7-H3 (CD276) research and drug development. Molecular Cancer. 2023 Mar 2​
• Huang H, Lu J, Aukhil I, Yu C, Bhut B, Marchesan J, Pirih F, Chang J. FBXO11 regulates bone development. Bone. 2023 May;170:116709. Epub 2023 Mar 1.​
• Costello HM, Juffre A, Cheng KY, Bratanatawira P, Crislip GR, Zietara A, Spires DR, Staruschenko A, Douma LG, Gumz ML. The circadian clock protein PER1 is important in maintaining endothelin axis regulation in Dahl salt-sensitive rats. Canadian Journal of Physiology and Pharmacology. 2023 Mar 1​

February

• Helsley RN, Park SH, Vekaria HJ, Sullivan PG, Conroy LR, Sun RC, Romero MDM, Herrero L, Bons J, King CD, Rose J, Meyer JG, Schilling B, Kahn CR, Softic S. Ketohexokinase-C regulates global protein acetylation to decrease carnitine palmitoyltransferase 1a-mediated fatty acid oxidation. Journal of Hepatology. 2023 Feb 21​

January

• Wolff CA, Gutierrez-Monreal MA, Meng L, Zhang X, Douma LG, Costello HM, Douglas CM, Ebrahimi E, Pham A, Oliveira AC, Fu C, Nguyen A, Alava BR, Hesketh SJ, Morris AR, Endale MM, Crislip GR, Cheng KY, Schroder EA, Delisle BP, Bryant AJ, Gumz ML, Huo Z, Liu AC, Esser KA. Defining the age-dependent and tissue-specific circadian transcriptome in male mice. Cell Reports. 2023 Jan 9. Epub ahead of print. 
• Lei J, Mahar R, Chang MC, Collins J, Merritt ME, Garrett TJ, Yost RA. Segmented Flow Strategies for Integrating Liquid Chromatography-Mass Spectrometry with Nuclear Magnetic Resonance for Lipidomics. Analytical Chemistry. 2023 Jan 11. Epub ahead of print. 
• Combs J, Bozdag M, Cravey LD, Kota A, McKenna R, Angeli A, Carta F, Supuran CT. New Insights into Conformationally Restricted Carbonic Anhydrase Inhibitors. Molecules. 2023 Jan 16 
• Costello HM, Crislip GR, Cheng KY, Lynch IJ, Juffre A, Bratanatawira P, Mckee A, Thelwell RS, Mendez VM, Wingo CS, Douma LG, Gumz ML. Adrenal-Specific KO of the Circadian Clock Protein BMAL1 Alters Blood Pressure Rhythm and Timing of Eating Behavior. Function (Oxford Academic Press). 2023 Jan 9
• Staklinski SJ, Chang MC, Ahrens-Nicklas RC, Kaur S, Stefanatos AK, Dudenhausen EE, Merritt ME, Kilberg MS. Characterizing asparagine synthetase deficiency variants in lymphoblastoid cell lines. Journal of Inherited Metabolic Disease Reports. 2023 Jan 5​

2022

December

• Staklinski SJ, Snanoudj S, Guerrot AM, Vanhulle C, Lecoquierre F, Bekri S, Kilberg MS. Analysis of Enzyme Activity and Cellular Function for the N80S and S480F Asparagine Synthetase Variants Expressed in a Child with Asparagine Synthetase Deficiency. International Journal of Molecular Sciences. 2022 Dec 29 
• Kaushik AK, Tarangelo A, Boroughs LK, Ragavan M, Zhang Y, Wu CY, Li X, Ahumada K, Chiang JC, Tcheuyap VT, Saatchi F, Do QN, Yong C, Rosales T, Stevens C, Rao AD, Faubert B, Pachnis P, Zacharias LG, Vu H, Cai F, Mathews TP, Genovese G, Slusher BS, Kapur P, Sun X, Merritt M, Brugarolas J, DeBerardinis RJ. In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma. Science Advances. 2022 Dec 16 
• Arora R, Kim JH, Getu AA, Angajala A, Chen YL, Wang B, Kahn AG, Chen H, Reshi L, Lu J, Zhang W, Zhou M, Tan M. MST4: A Potential Oncogene and Therapeutic Target in Breast Cancer. Cells. 2022 Dec 15 
• Newcomb ESP, Douma LG, Morris LA, Bloom LB. The Escherichia coli clamp loader rapidly remodels SSB on DNA to load clamps. Nucleic Acids Research. 2022 Dec 13. Epub ahead of print.  
• Weeks-Pollenz SJ, Ali Y, Morris L, Sutera VA, Dudenhausen EE, Hibnick M, Lovett ST, Bloom LB. Characterization of the Escherichia coli XPD/Rad3 iron-sulfur helicase YoaA in complex with the DNA polymerase III clamp loader subunit chi (χ). Journal of Biological Chemistry. 2022 Dec 9. Epub ahead of print. 
• Khattri RB, Puglise J, Ryan TE, Walter GA, Merritt ME, Barton ER. Isolated murine skeletal muscles utilize pyruvate over glucose for oxidation. Metabolomics. 2022 Dec 8. 

November

• Costello HM, Juffre AC, Cheng KY, Bratanatawira P, Crislip GR, Spires DR, Zietara AP, Staruschenko A, Douma LG, Gumz ML. The Circadian Clock Protein PER1 is Important in Maintaining Endothelin Axis Regulation in Dahl Salt Sensitive Rats. Canadian Journal of Physiology and Pharmacology. 2022 Nov 30. Epub ahead of print.   
• Georgiou-Karistianis N, Corben LA, Reetz K, Adanyeguh IM, Corti M, Deelchand DK, Delatycki MB, Dogan I, Evans R, Farmer J, França MC, Gaetz W, Harding IH, Harris KS, Hersch S, Joules R, Joers JJ, Krishnan ML, Lax M, Lock EF, Lynch D, Mareci T, Muthuhetti Gamage S, Pandolfo M, Papoutsi M, Rezende TJR, Roberts TPL, Rosenberg JT, Romanzetti S, Schulz JB, Schilling T, Schwarz AJ, Subramony S, Yao B, Zicha S, Lenglet C, Henry PG. A natural history study to track brain and spinal cord changes in individuals with Friedreich’s ataxia: TRACK-FA study protocol. PLOS One. 2022 Nov 21. 
• Sharma G, Maptue N, Rahim M, Trigo Mijes ML, Hever T, Wen X, Funk AM, Malloy CR, Young JD, Khemtong C. Oxidation of hyperpolarized [1-13 C]pyruvate in isolated rat kidneys.NMR in Biomedicine. 2023 Mar; Epub 2022 Nov 17.​
• Zietara A, Spires DR, Juffre A, Costello HM, Crislip GR, Douma LG, Levchenko V, Dissanayake LV, Klemens CA, Nikolaienko O, Geurts AM, Gumz ML, Staruschenko A. Knockout of the Circadian Clock Protein PER1 (Period1) Exacerbates Hypertension and Increases Kidney Injury in Dahl Salt-Sensitive Rats. Hypertension. 2022 Nov