2023
April
- Guijarro MV, Kellish PC, Dib PE, Paciaroni NG, Nawab A, Andring J, Kulemina L, Borrero NV, Modenutti C, Feely M, Nasri E, Seifert RP, Luo X, Bennett RL, Shabashvili D, Licht JD, McKenna R, Roitberg A, Huigens Iii RW, Kaye FJ, Zajac-Kaye M. First-in-class multifunctional TYMS non-classical antifolate inhibitor with potent in vivo activity that prolongs survival. Journal of Clinical Investigation Insight. 2023 Apr 25. Epub ahead of print.
- Chang MC, Staklinski SJ, Malut VR, Pierre GL, Kilberg MS, Merritt ME. Metabolomic Profiling of Asparagine Deprivation in Asparagine Synthetase Deficiency Patient-Derived Cells. Nutrients. 2023 Apr 18.
- Chin Y, Gumilar KE, Li XG, Tjokroprawiro BA, Lu CH, Lu J, Zhou M, Sobol RW, Tan M. Targeting HSF1 for cancer treatment: mechanisms and inhibitor development. Theranostics. 2023 Apr 17.
- Sheng P, Li L, Li T, Wang Y, Hiers NM, Mejia JS, Sanchez JS, Zhou L, Xie M. Screening of Drosophila microRNA-degradation sequences reveals Argonaute1 mRNA’s role in regulating miR-999. Nature Communications. 2023 Apr 13;14(1):2108.
- Gobin C, Inkabi S, Lattimore CC, Gu T, Menefee JN, Rodriguez M, Kates H, Fields C, Bian T, Silver N, Xing C, Yates C, Renne R, Xie M, Fredenburg KM. Investigating miR-9 as a mediator in laryngeal cancer health disparities. Frontiers in Oncology. 2023 Apr 4;13:1096882.
- Logan GJ, Mietzsch M, Khandekar N, D’Silva A, Anderson D, Mandwie M, Hsi J, Nelson AR, Chipman P, Jackson J, Schofield P, Christ D, Goodnow CC, Reed JH, Farrar MA, McKenna R, Alexander IE. Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy. Molecular Therapy. 2023 Apr 3:S1525-0016(23)00165-X.
March
- Johnston JG, Welch AK, Cain BD, Sayeski PP, Gumz ML, Wingo CS. Aldosterone: Renal Action and Physiological Effects. Comprehensive Physiology. 2023 Mar 30;13(2):4409-4491.
- Chen Z, Zhou K, Xue J, Small A, Xiao G, Nguyen LXT, Zhang Z, Prince E, Weng H, Huang H, Zhao Z, Qing Y, Shen C, Li W, Han L, Tan B, Su R, Qin H, Li Y, Wu D, Gu Z, Ngo VN, He X, Chao J, Leung K, Wang K, Dong L, Qin X, Cai Z, Sheng Y, Chen Y, Wu X, Zhang B, Shi Y, Marcucci G, Qian Z, Xu M, Müschen M, Chen J, Deng X. Phosphorylation stabilized TET1 acts as an oncoprotein and therapeutic target in B cell acute lymphoblastic leukemia. Science Translational Medicine. 2023 Mar 29
- Kamson DO, Chinnasamy V, Grossman SA, Bettegowda C, Barker PB, Stacpoole PW, Oeltzschner G. In-vivo magnetic resonance spectroscopy of lactate as a non-invasive biomarker of dichloroacetate activity in cancer and non-cancer central nervous system disorders. Frontiers in Oncology 2023 Mar 17;13:1077461.
- Porter JM, Oswald MS, Sharma A, Emmanuel S, Kansol A, Bennett A, McKenna R, Smith JG. A Single Surface-Exposed Amino Acid Determines Differential Neutralization of AAV1 and AAV6 by Human Alpha-Defensins. Journal of Virology. 2023 Mar 14: Epub ahead of print.
- Combs LR, Combs J, McKenna R, Toth Z. Protein Degradation by Gammaherpesvirus RTAs: More Than Just Viral Transactivators. Viruses. 2023 Mar 11;15(3):730.
- Frost CJ, Ramirez-Mata A, Khattri RB, Merritt ME, Frost SC. Effects of β-caryophyllene and oxygen availability on cholesterol and fatty acids in breast cancer cells. PLoS One. 2023 Mar 9
- Lee S, Devanney NA, Golden LR, Smith CT, Schwartz JL, Walsh AE, Clarke HA, Goulding DS, Allenger EJ, Morillo-Segovia G, Friday CM, Gorman AA, Hawkinson TR, MacLean SM, Williams HC, Sun RC, Morganti JM, Johnson LA. APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge. Cell Reports. 2023 Mar 3
- Getu AA, Tigabu A, Zhou M, Lu J, Fodstad Ø, Tan M. New frontiers in immune checkpoint B7-H3 (CD276) research and drug development. Molecular Cancer. 2023 Mar 2
- Huang H, Lu J, Aukhil I, Yu C, Bhut B, Marchesan J, Pirih F, Chang J. FBXO11 regulates bone development. Bone. 2023 May;170:116709. Epub 2023 Mar 1.
- Costello HM, Juffre A, Cheng KY, Bratanatawira P, Crislip GR, Zietara A, Spires DR, Staruschenko A, Douma LG, Gumz ML. The circadian clock protein PER1 is important in maintaining endothelin axis regulation in Dahl salt-sensitive rats. Canadian Journal of Physiology and Pharmacology. 2023 Mar 1
February
- Helsley RN, Park SH, Vekaria HJ, Sullivan PG, Conroy LR, Sun RC, Romero MDM, Herrero L, Bons J, King CD, Rose J, Meyer JG, Schilling B, Kahn CR, Softic S. Ketohexokinase-C regulates global protein acetylation to decrease carnitine palmitoyltransferase 1a-mediated fatty acid oxidation. Journal of Hepatology. 2023 Feb 21
January
- Wolff CA, Gutierrez-Monreal MA, Meng L, Zhang X, Douma LG, Costello HM, Douglas CM, Ebrahimi E, Pham A, Oliveira AC, Fu C, Nguyen A, Alava BR, Hesketh SJ, Morris AR, Endale MM, Crislip GR, Cheng KY, Schroder EA, Delisle BP, Bryant AJ, Gumz ML, Huo Z, Liu AC, Esser KA. Defining the age-dependent and tissue-specific circadian transcriptome in male mice. Cell Reports. 2023 Jan 9. Epub ahead of print.
- Lei J, Mahar R, Chang MC, Collins J, Merritt ME, Garrett TJ, Yost RA. Segmented Flow Strategies for Integrating Liquid Chromatography-Mass Spectrometry with Nuclear Magnetic Resonance for Lipidomics. Analytical Chemistry. 2023 Jan 11. Epub ahead of print.
- Combs J, Bozdag M, Cravey LD, Kota A, McKenna R, Angeli A, Carta F, Supuran CT. New Insights into Conformationally Restricted Carbonic Anhydrase Inhibitors. Molecules. 2023 Jan 16
- Costello HM, Crislip GR, Cheng KY, Lynch IJ, Juffre A, Bratanatawira P, Mckee A, Thelwell RS, Mendez VM, Wingo CS, Douma LG, Gumz ML. Adrenal-Specific KO of the Circadian Clock Protein BMAL1 Alters Blood Pressure Rhythm and Timing of Eating Behavior. Function (Oxford Academic Press). 2023 Jan 9
- Staklinski SJ, Chang MC, Ahrens-Nicklas RC, Kaur S, Stefanatos AK, Dudenhausen EE, Merritt ME, Kilberg MS. Characterizing asparagine synthetase deficiency variants in lymphoblastoid cell lines. Journal of Inherited Metabolic Disease Reports. 2023 Jan 5
2022
December
- Staklinski SJ, Snanoudj S, Guerrot AM, Vanhulle C, Lecoquierre F, Bekri S, Kilberg MS. Analysis of Enzyme Activity and Cellular Function for the N80S and S480F Asparagine Synthetase Variants Expressed in a Child with Asparagine Synthetase Deficiency. International Journal of Molecular Sciences. 2022 Dec 29
- Kaushik AK, Tarangelo A, Boroughs LK, Ragavan M, Zhang Y, Wu CY, Li X, Ahumada K, Chiang JC, Tcheuyap VT, Saatchi F, Do QN, Yong C, Rosales T, Stevens C, Rao AD, Faubert B, Pachnis P, Zacharias LG, Vu H, Cai F, Mathews TP, Genovese G, Slusher BS, Kapur P, Sun X, Merritt M, Brugarolas J, DeBerardinis RJ. In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma. Science Advances. 2022 Dec 16
- Arora R, Kim JH, Getu AA, Angajala A, Chen YL, Wang B, Kahn AG, Chen H, Reshi L, Lu J, Zhang W, Zhou M, Tan M. MST4: A Potential Oncogene and Therapeutic Target in Breast Cancer. Cells. 2022 Dec 15
- Newcomb ESP, Douma LG, Morris LA, Bloom LB. The Escherichia coli clamp loader rapidly remodels SSB on DNA to load clamps. Nucleic Acids Research. 2022 Dec 13. Epub ahead of print.
- Weeks-Pollenz SJ, Ali Y, Morris L, Sutera VA, Dudenhausen EE, Hibnick M, Lovett ST, Bloom LB. Characterization of the Escherichia coli XPD/Rad3 iron-sulfur helicase YoaA in complex with the DNA polymerase III clamp loader subunit chi (χ). Journal of Biological Chemistry. 2022 Dec 9. Epub ahead of print.
- Khattri RB, Puglise J, Ryan TE, Walter GA, Merritt ME, Barton ER. Isolated murine skeletal muscles utilize pyruvate over glucose for oxidation. Metabolomics. 2022 Dec 8.
November
- Costello HM, Juffre AC, Cheng KY, Bratanatawira P, Crislip GR, Spires DR, Zietara AP, Staruschenko A, Douma LG, Gumz ML. The Circadian Clock Protein PER1 is Important in Maintaining Endothelin Axis Regulation in Dahl Salt Sensitive Rats. Canadian Journal of Physiology and Pharmacology. 2022 Nov 30. Epub ahead of print.
- Georgiou-Karistianis N, Corben LA, Reetz K, Adanyeguh IM, Corti M, Deelchand DK, Delatycki MB, Dogan I, Evans R, Farmer J, França MC, Gaetz W, Harding IH, Harris KS, Hersch S, Joules R, Joers JJ, Krishnan ML, Lax M, Lock EF, Lynch D, Mareci T, Muthuhetti Gamage S, Pandolfo M, Papoutsi M, Rezende TJR, Roberts TPL, Rosenberg JT, Romanzetti S, Schulz JB, Schilling T, Schwarz AJ, Subramony S, Yao B, Zicha S, Lenglet C, Henry PG. A natural history study to track brain and spinal cord changes in individuals with Friedreich’s ataxia: TRACK-FA study protocol. PLOS One. 2022 Nov 21.
- Sharma G, Maptue N, Rahim M, Trigo Mijes ML, Hever T, Wen X, Funk AM, Malloy CR, Young JD, Khemtong C. Oxidation of hyperpolarized [1-13 C]pyruvate in isolated rat kidneys.NMR in Biomedicine. 2023 Mar; Epub 2022 Nov 17.
- Zietara A, Spires DR, Juffre A, Costello HM, Crislip GR, Douma LG, Levchenko V, Dissanayake LV, Klemens CA, Nikolaienko O, Geurts AM, Gumz ML, Staruschenko A. Knockout of the Circadian Clock Protein PER1 (Period1) Exacerbates Hypertension and Increases Kidney Injury in Dahl Salt-Sensitive Rats. Hypertension. 2022 Nov